Authors: Alessandro Sartorio C Lafortuna P Capodaglio V Vangeli M V Narici G Faglia
Publish Date: 2014/03/11
Volume: 24, Issue: 11, Pages: 882-886
Abstract
The aim of the present study was to evaluate the effects of a 16week progressive highintensity strength training HIST program on peripheral markers of bone turnover bone Gla protein BGP bone alkaline phosphatase BAP Nterminal propeptide of type I procollagen PINP Cterminal crosslinked telopeptide of type I collagen ICTP in healthy elderly men over 65 yr of age Thirty healthy men aged 65–81 yr performing light to moderate daily physical activity were randomly divided into two groups Group 1 no=16 followed a supervised 16week progressive HIST program while subjects of group 2 no=14 used as controls were requested to maintain their habitual level of physical activity for 16 weeks HIST program consisted of 6 different sets of exercise 2 involving the major muscle groups of the lower limb and 4 involving those of the upper limb Three sessions/week during which 10 repetitions of each exercise set were completed were performed Lower limb exercises shifted from 50 to 80 of the one maximal repetition 1MR during the first month of the protocol and were thereafter maintained at an intensity of 80 1MR throughout the training Upper limb exercises shifted from 40 to 65 of 1MR with a similar pattern All sessions were preceded by 15 min of cycloergometer exercise at 50 of maximal oxygen uptake and by a warmup of 15 repetitions at 20 of 1MR of each exercise set The HIST program did not significantly change BGP mean±SE before 156±12 μg/l vs after 160±12 μg/l NS and PINP levels before 446±67 μg/l vs after 431±60 μg/l NS On the contrary serum BAP significantly increased before 502±61 IU/l vs after 623±70 IU/l p0001 and serum ICTP slightly reduced before 40±03 μg/l vs after 38±03 μg/l p005 When bone turnover was expressed as the ratio between bone formation to bone resorption BAP/ICTP ratio a significant improvement in this ratio was found in all subjects of group 1 before 129±13 IU/μg vs after 173±15 IU/μg p00001 while no significant changes were observed in Group 2 No significant changes of IGFI levels were observed after the HIST program before 949±94 μg/l vs after 899±97 μg/l No significant changes of BGP PINP BAP ICTP BAPICTP ratio and IGFI levels were observed in controls group 2 during the 16 weeks of observation Although the positive effects of a progressive HIST program on BAP levels and BAPICTP ratio seem promising the support of bone mass measurement and the determination of other bone markers are requested to better identify exercise protocol duration intensity for elderly people
Keywords: