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Title of Journal: J Endocrinol Invest

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Abbravation: Journal of Endocrinological Investigation

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Springer International Publishing

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DOI

10.1002/pssb.19670230252

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1720-8386

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The dissociation of the exaggerated prolactin and

Authors: I M Spitz B Levitt E ZylberHaran M Haas Y Livshin
Publish Date: 2014/04/01
Volume: 6, Issue: 4, Pages: 273-276
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Abstract

PRL and TSH secretion has been evaluated in 11 patients with seminiferous tubule failure and 9 controls When compared to the controls the patients had increased basal FSH TSH and PRL levels However LH E2 T and thyroid hormone levels were similar to the controls Both groups were given two pulses of TRH 200 μg at 30 min intervals Following the initial pulse of TRH the patients demonstrated exaggerated TSH and PRL responses The administration of a second pulse of TRH led to a further increment of TSH secretion in the patients There was however no PRL response to the second TRH pulse in either patients or controls although mean PRL levels remained significantly greater in the patients

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