Authors: Paul Merritt Elliot Hirshman John Hsu Michael Berrigan
Publish Date: 2004/07/28
Volume: 177, Issue: 3, Pages: 336-343
Abstract
Midazolam is a benzodiazepine which produces a dense anterograde amnesia while permitting relatively wellpreserved shortterm memory semantic retrieval and other higher cognitive functions Given these preserved abilities we were interested in whether or not participants given midazolam would be aware of this anterograde amnesiaIn the present experiment participants were given midazolam in one testing session and a saline placebo in another Participants provided judgmentsoflearning JOLs immediately following study of cuetarget pairs During the test phase of the experiment confidence levels and feelingofknowing FOK judgments were collectedAlthough cued recall performance was substantially impaired in the midazolam condition mean JOLs were unaffected indicating participants had little insight into their impairment during the study phase Participants were relatively accurate in confidence levels and FOK judgments in the midazolam condition
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