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Title of Journal: Psychopharmacology

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Abbravation: Psychopharmacology

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Springer-Verlag

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10.1016/0098-1354(90)87013-f

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1432-2072

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Influence of nicotine on positive affect in anhedo

Authors: Jessica Werth Cook Bonnie Spring Dennis McChargue
Publish Date: 2007/02/03
Volume: 192, Issue: 1, Pages: 87-95
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Abstract

The possibility that individuals administer nicotine to selfregulate persistent negative affect has received interest as a possible explanation for the high prevalence of affectively vulnerable smokers Relatively overlooked however is the possibility that smokers might also selfadminister nicotine to elevate low positive affectRandom effects regression showed a significant anhedonia by conditionbytime interaction t181=−201 p = 004 supporting the hypothesis that anhedonia moderated nicotine’s effect on changes in positive affect Simple effect analyses showed a significant conditionbytime interaction among high anhedonic smokers t91= 247 p = 001 but not among less anhedonic smokers t91= 034 p = 073

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