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Title of Journal: Appl Microbiol Biotechnol

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Abbravation: Applied Microbiology and Biotechnology

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Springer-Verlag

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DOI

10.1002/pssb.2220850139

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1432-0614

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Yeast expression platforms

Authors: Erik Böer Gerhard Steinborn Gotthard Kunze Gerd Gellissen
Publish Date: 2007/10/09
Volume: 77, Issue: 3, Pages: 513-523
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Abstract

Yeasts provide attractive expression platforms They combine ease of genetic manipulations and the option for a simple fermentation design of a microbial organism with the capabilities of an eukaryotic organism to secrete and to modify a protein according to a general eukaryotic scheme For platform applications a range of yeast species has been developed during the last decades We present in the following review a selection of established and newly defined expression systems The review is concluded by the description of a widerange vector system that allows the assessment of the selected organisms in parallel for criteria like secretion or appropriate processing and modification in a given case

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