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Title of Journal: Appl Microbiol Biotechnol

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Abbravation: Applied Microbiology and Biotechnology

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Springer Berlin Heidelberg

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DOI

10.1007/s12199-012-0312-8

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1432-0614

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Silverdecorated orthorhombic nanotubes of lithium

Authors: Rahul S Diggikar Rajendra H Patil Sheetal B Kale Dipalee K Thombre Wasudeo N Gade Milind V Kulkarni Bharat B Kale
Publish Date: 2013/07/24
Volume: 97, Issue: 18, Pages: 8283-8290
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Abstract

Reoccurrence of infectious diseases and ability of pathogens to resist antibacterial action has raised enormous challenges which may possibly be confronted by nanotechnology routes In the present study uniformly embedded silver nanoparticles in orthorhombic nanotubes of lithium vanadium oxide LiV2O5/Ag were explored as an impeder of bacterial growth and biofilm The LiV2O5/Ag nanocomposites have impeded growth of Grampositive Bacillus subtilis NCIM 2063 and Gramnegative Escherichia coli NCIM 2931 at 60 to 120 μg/mL It also impeded the biofilm in Pseudomonas aeruginosa NCIM 2948 at 125 to 25 μg/mL Impedance in the growth and biofilm occurs primarily by direct action of the nanocomposites on the cell surfaces of test organisms as revealed by surface perturbation in scanning electron microscopy As the metabolic growth and biofilm formation phenomena of pathogens play a central role in progression of pathogenesis LiV2O5/Ag nanocompositebased approach is likely to curb the menace of reoccurrence of infectious diseases Thus LiV2O5/Ag nanocomposites can be viewed as a promising candidate in biofabrication of biomedical materialsThis work was financially supported by University Grants Commission New Delhi to RD under FIP scheme File No 3434/08 and the work was carried out in the CMET Pune India and Department of Biotechnology University of Pune DT would like to thank DSTPURSE Programme RP would like to thanks Departmental Research and Development Grant for financial assistance to the present work

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