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Title of Journal: J Radioanal Nucl Chem

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Abbravation: Journal of Radioanalytical and Nuclear Chemistry

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Springer Netherlands

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DOI

10.1016/0006-8993(81)90350-4

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ISSN

1588-2780

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Production and quality control of Superscript16

Authors: Alireza KhoramiMoghadam Amir Reza Jalilian Kamal Yavari Bahram Bolouri Ali BahramiSamani Mohammad GhannadiMaragheh
Publish Date: 2012/02/04
Volume: 292, Issue: 3, Pages: 1065-1073
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Abstract

Antiangiogenic monoclonal antibodies in combination with therapeutic radionuclides are potential targeted therapy agents in cancer In this study bevacizumab was successively labeled with 166HoHoCl3 after conjugation with DOTANHSester with a radiochemical purity of higher than 95 RTLC The conjugates were purified by molecular filtration the average number of DOTA conjugated per mAb was calculated and total concentration was determined by spectrophotometric method and the average chelate to antibody ratio c/a for the conjugate used in this study was 581 and protein integrity experiments SDSPAGE The biodistribution studies in wildtype rats demonstrate a similar pattern to the other radiolabeled antivascular endothelial growth factor A VEGFA immunoconjugates 166HoDOTAbevacizumab is a potential compound for therapy/imaging of VEGFA expression in oncology

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Other Papers In This Journal:
  1. Potentiostatic electro-deposition of 241 Am using room temperature ionic liquids
  2. Solid phase microextraction sampling of high explosive residues in the presence of radionuclides and radionuclide surrogate metals
  3. Comparative study of inorganic elements determination in whole blood from Crioula breed horse by EDXRF and NAA analytical techniques
  4. Terrestrial gamma dose rate in Pahang state Malaysia
  5. PIXE analysis for bioaccumulation studies of trace elements
  6. Radioactive impact of a bauxite beneficiation plant in the Itea Gulf (Gulf of Corinth, Greece)
  7. Quantitative analysis of neodymium, uranium, and palladium in nitric acid solution by reflection absorption spectrophotometry
  8. First results studying the transmutation of 129 I, 237 Np, 238 Pu, and 239 Pu in the irradiation of an extended nat U/Pb-assembly with 2.52 GeV deuterons
  9. Rapid measurement of 241 Pu activity at environmental levels using low-level liquid scintillation analysis
  10. Estimating emission source of lead using 210 Pb specific activity ( 210 Pb/Pb) and zinc as tracers in Slovenian forest soils
  11. Modified TTA method for the determination of plutonium
  12. Application of radiometric method for element migration determination from plastic packaging to food
  13. Study of Doppler broadening of gamma-ray spectra in 14-MeV neutron activation analysis
  14. Radiological assessment of pharmaceutical clays
  15. Controllable polymerization of poly-DVB–VBC– g– AO resin via surface-initiated atom transfer radical polymerization for uranium removal
  16. Cesium uptake by Ca/Mg bentonite: evaluation of sorption experiments by a multicomponent two-site ion-exchange model
  17. The isomeric ratio of fragment 135 Xe from photofission of 233 U induced by 23.5 MeV bremsstrahlung
  18. The operator dose assessment of landmine detection systems using the neutron backscattering method
  19. Reassessment of doses in TLD100 by measuring the residual dose
  20. Characterization of nano-iron oxyhydroxides and their application in UO 2 2+ removal from aqueous solutions
  21. Insights into sorption species of Eu(III) on γ-Al 2 O 3 and bentonite under different pH: Studies at macro- and micro-scales
  22. Alpha and gamma radiolysis of nuclear solvent extraction ligands used for An(III) and Ln(III) separations
  23. Rapid separation of actinides and radiostrontium in vegetation samples
  24. Kinetics for extraction of zirconium and hafnium in DIBK-P350 system
  25. Neutral 99m Tc(CO) 3 complexes of “clicked” nitroimidazoles for the detection of tumor hypoxia
  26. Evaluation study on silica/polymer-based CA-BTP adsorbent for the separation of minor actinides from simulated high-level liquid wastes
  27. Evaluation study on silica/polymer-based CA-BTP adsorbent for the separation of minor actinides from simulated high-level liquid wastes
  28. Source injection distribution functions for alarm algorithm testing
  29. Distribution of 99 Tc and 129 I in the vicinity of underground nuclear tests at the Nevada Test Site
  30. Preparation and preliminary evaluation of 211 At-labeled amidobisphophonates
  31. Description and application of a novel glucagon-like peptide-1 (GLP-1) radioimmunoassay
  32. Extraction of uranyl ion into ionic liquid by N , N , N ′, N ′-tetrabutylsuccinamide and spectroscopic study of uranyl complex
  33. Simultaneous determination and uptake assessment of selected radionuclides in plants grown in substrate contaminated with U-mill tailings
  34. Production of 95m Tc for Compton camera imaging
  35. Instrumental neutron activation analysis of hafnium in zirconium metal using internal standardization
  36. Radionuclides in redistributed sediments and ash from the Las Conchas fire in Northern New Mexico
  37. Fallout of 7 Be in Damascus City
  38. Investigation of deuteron-induced reactions on nat Gd up to 30 MeV: possibility of production of medically relevant 155 Tb and 161 Tb radioisotopes
  39. Neutron activation analysis of air-filters collected in Spokane, WA
  40. Determination of trace elements in blood samples of patients affected by multiple sclerosis from Iran by neutron activation analysis
  41. Rapid method for determination of plutonium, americium and curium in large soil samples
  42. Impact of environmental conditions on the sorption behavior of radiocobalt onto montmorillonite
  43. Impact of environmental conditions on the sorption behavior of radiocobalt onto montmorillonite
  44. Determination of silver using cyclic epithermal neutron activation analysis
  45. 210 Pb and 210 Po radionuclides in the urban air of Lodz, Poland
  46. Comparative evaluation of two substituted diglycolamide extractants for ‘actinide partitioning’
  47. Residence time distribution study in a pilot-scale gas–solid fluidized bed reactor using radiotracer technique
  48. Measurement of 7 Be inventory in the outer Songkhla lagoon, Thailand
  49. Radio-immunoconjugated, Dox-loaded, surface-modified superparamagnetic iron oxide nanoparticles (SPIONs) as a bioprobe for breast cancer tumor theranostics
  50. The development of a material for uranium sorption in NH 3 /N environments
  51. Micro-PIXE analysis of bioconductive hydroxyapatite coatings on titanium alloy
  52. Sorption of technetium on glutaraldehyde crosslinked chitosan
  53. Variation in k 0 neutron flux parameters after replacement of the beryllium reflector and graphite wedge at the University of Missouri Research Reactor
  54. Evaluation of interferences on measurements of 90 Sr/ 90 Y by TDCR Cherenkov counting technique
  55. Gamma spectrometer measurements of microgram quantities of plutonium using uranium L X-rays in the 13–21 keV region
  56. Agricultural management, season and trace elements effects on volatile oil production from Melissa officinalis L. (Lemon balm)
  57. The urgent requirement for new radioanalytical certified reference materials for nuclear safeguards, forensics, and consequence management
  58. Non-destructive bulk analysis of the Buggenum sword by neutron resonance capture analysis and neutron diffraction
  59. Amidoxime functionalized Trametes trogii pellets for removal of uranium(VI) from aqueous medium
  60. Column studies for the separation of 99m Tc using activated carbon
  61. Green methods for the radiochemical separations of no-carrier-added 61 Cu, 62 Zn from 7 Li irradiated cobalt target
  62. Neutron dosimetry device using PADC nuclear track detectors
  63. Primary evaluation of a nickel-chlorophyll derivative as a multimodality agent for tumor imaging and photodynamic therapy
  64. Accelerator mass spectrometry of actinides
  65. Sorption of aqueous palladium onto synthetic hydroxyapatite
  66. Sorption of cesium from water solutions on potassium nickel hexacyanoferrate-modified Agaricus bisporus mushroom biomass
  67. Characterization of black volcanites from the Limay river basin, Patagonia, Argentina, using energy dispersive X-ray fluorescence spectrometry: an aid to infer human group mobility
  68. Natural radioactivity level and radiological hazard assessment of commonly used building material in Xining, China
  69. Extraction separation of Am(III) and Eu(III) using divalent quadridentate Schiff bases-bis-salicylaldehyde ethylenediamine
  70. Tritium analysis in building dismantling process using digital autoradiography
  71. Synthesis of [ 188 ReX(CO) 5 ] ( X = Cl, Br, and I)
  72. Monitoring of caesium-137 in surface seawater and seafood in both the Irish and North Seas: trends and observations
  73. K-shell fluorescence yields and their uncertainties for use in hybrid K-edge densitometry
  74. INAA of enamel and dentine samples of a group of children and adults: A comparative study
  75. Radiochemical determination of nuclear data for theory and applications
  76. Ammonium uranyl carbonate (AUC) based process of simultaneous partitioning and reconversion for uranium and plutonium in fast breeder reactors (FBRs) fuel reprocessing
  77. Local delivery of rhenium-188 colloid into hepatic tumor sites in rats using thermo-sensitive chitosan hydrogel: effects of gelling time of chitosan as delivery system
  78. Reduction of U 3 O 8 to U by a metallic reductant, Li
  79. Elemental contents in hair of children from Zanzibar in Tanzania as bio-indicator of their nutritional status
  80. One-dimensional mapping of gamma emitting radionuclides in support of forensic examination
  81. Extraction of Am(III) and Eu(III) with dialkyldi (or mono) thiophosphinic (or phosphoric) acids
  82. Effect of natural gas usage on indoor radon levels
  83. In vitro evaluation of apoptosis detection by 99m Tc-tetrofosmin in MCF-7 breast cancer cell line
  84. Synthesis and biodistribution of 99m Tc(CO) 3 -DMSA-MIBI in mice
  85. Sorption of radionuclides and metals to graphene oxide and magnetic graphene oxide
  86. Production of cerium-141 using ceria and nanoceria powder: a potential radioisotope for simultaneous therapeutic and diagnostic applications
  87. Determination of 90 Sr and 210 Pb in deer bone samples by liquid scintillation counting after ion-exchange procedures
  88. Solid phase separation and ICP-OES/ICP-MS determination of rare earth impurities in nuclear grade uranium oxide
  89. Further results in search for transuranium elements in effluents discharged to air from nuclear power plants
  90. Electrochemical de-chlorination/transformation of metal chloride for the preparation of NZP structure product
  91. Plutonium hydrolysis and the double double-point
  92. Association and migration behavior of trace metals with humus colloidal particles in aquatic subsurface medium
  93. The production of 172 Tm by triple neutron capture in nuclear reactors
  94. Characterization of long-term dose stability of N -isopropylacrylamide polymer gel dosimetry
  95. Isocratic anion exchange separations of Group V elements
  96. Application of energy dispersive X-ray fluorescence for the determination of metallic impurities in ThO 2
  97. High quality actinide targets
  98. Nonequilibrium method for estimating the first hydrolysis constant of tetravalent plutonium
  99. Treatment of low level radioactive liquid wastes using composite ion-exchange resins based on polyurethane foam
  100. The production of 103 Pd and 109 Cd from a proton irradiated tandem nat Ag/ nat Ag targets
  101. Synergistic extraction of uranium with mixtures of PC88A and neutral oxodonors
  102. True coincidence summing corrections in point and extended sources
  103. Estimation of natural potassium concentration in Romanian males by in vivo gamma-ray spectrometry measurements
  104. Investigation of radiocesium biokinetics in Manila clam ( Ruditapes philippinarum )
  105. Age-dating methodology for 137 Cs ceramic sources
  106. Screening of biosorption bacteria tolerance towards copper and cadmium from oil sludge pond
  107. Study of arsenic (As) mobilization in the Ganga Alluvial Plain using neutron activation analysis
  108. Detection of additional impurities in the UV-chromatogram of l -[ S -methyl- 11 C]methionine
  109. Wastewater treatment with ionizing radiation
  110. Proficiency test for radioactivity measurements in nuclear medicine
  111. Labeling of atenolol with radioactive iodine-125 using N -bromosuccinimide and hydrogen peroxide as oxidizing agents
  112. In situ preparation of magnetic chitosan resins functionalized with triethylene-tetramine for the adsorption of uranyl(II) ions
  113. Application of simulated standard spectra for the analysis of complex sample spectra from NaI(Tl) detectors
  114. Real-time stack monitoring at the BaTek medical isotope production facility
  115. A new method for the determination of low-level actinium-227 in geological samples
  116. Production of 223 Ra from 226 Ra in Tehran Research Reactor for treatment of bone metastases
  117. Distribution and identification of Plutonium(IV) species in tri- n -butyl phosphate/HNO 3 extraction system containing acetohydroxamic acid
  118. A software package using a mesh-grid method for simulating HPGe detector efficiencies
  119. Evaluating adsorption ability of granite to radioselenium by chemical sequential extraction
  120. Determination of 90 Sr in bone samples using molecular recognition technology product AnaLig ® Sr-01
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