Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Appl Biochem Biotechnol

Search In Journal Title:

Abbravation: Applied Biochemistry and Biotechnology

Search In Journal Abbravation:

Publisher

Humana Press Inc

Search In Publisher:

DOI

10.1016/j.amjmed.2003.12.029

Search In DOI:

ISSN

1559-0291

Search In ISSN:
Search In Title Of Papers:

Application of Response Surface Method for Studyin

Authors: Syed Ubaid Ahmed Sudheer Kumar Singh Ashok Pandey Sanjit Kanjilal Ruchipad B N Prasad
Publish Date: 2008/05/15
Volume: 152, Issue: 1, Pages: 108-116
PDF Link

Abstract

To study the effect of agitation speed rpm and dissolved oxygen concentration DO on the production of gamma linolenic acid by Mucor sp RRL001 a central composite design experiment was performed in a 5L stirred tank bioreactor The design consisted of a total of 10 runs consisting of runs at five levels for each factor and was divided in two blocks The ANOVA analysis and Pareto chart of effects suggested agitation speed p = 00142 linear effect and DO concentration p = 00342 quadratic effects were significant factors with significant contribution to the response The validation run based on the optimum production zone in response surface plot resulted in the maximum 3503 mg l−1 GLA yield as compared with model predicted value of 3407 mg l−1 The study suggests that agitation rate is having more pronounced effect on GLA yield than dissolved oxygen concentration by ensuring enhanced mass transfer and by preventing wall growth at elevated agitation speed Also it shows that higher GLA yields can be obtained in a simple medium at moderate oxygen saturation and that the Mucor sp RRL001 is resistant to high agitation linked shear stress and suitable for GLA production at higher scale

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Hydrodynamic Characterization of a Column-type Prototype Bioreactor
  2. Solid-state Fermentation for Enhanced Production of Laccase using Indigenously Isolated Ganoderma sp.
  3. Production of Thermostable Lipase by Thermomyces lanuginosus on Solid-State Fermentation: Selective Hydrolysis of Sardine Oil
  4. Expression, Purification, and Characterization of Endo-β- N -Acetylglucosaminidase H Using Baculovirus-Mediated Silkworm Protein Expression System
  5. Exhausted Jackknife Validation Exemplified by Prediction of Temperature Optimum in Enzymatic Reaction of Cellulases
  6. Intrinsic Characteristics of Cr 6+ -Resistant Bacteria Isolated from an Electroplating Industry Polluted Soils for Plant Growth-Promoting Activities
  7. Phytase Production and Development of an Ideal Dephytinization Process for Amelioration of Food Nutrition Using Microbial Phytases
  8. Cunninghamella as a Microbiological Model for Metabolism of Histamine H 3 Receptor Antagonist 1-[3-(4- tert -Butylphenoxy)propyl]piperidine
  9. Synthesis, Characterization, and Oil Recovery Application of Biosurfactant Produced by Indigenous Pseudomonas aeruginosa WJ-1 Using Waste Vegetable Oils
  10. Regeneration-Based Quantification of Coumarins (Scopoletin and Scoparone) in Abutilon indicum In Vitro Cultures
  11. Identification of New Dominant-Negative Mutants of Anthrax Protective Antigen Using Directed Evolution
  12. Galanthamine and Related Alkaloids Production by Leucojum aestivum L. Shoot Culture using a Temporary Immersion Technology
  13. A Study on the Stability and Enzymatic Activity of Yeast Alcohol Dehydrogenase in Presence of the Self-Assembling Block Copolymer Poloxamer 407
  14. Lignin Peroxidase from Streptomyces viridosporus T7A: Enzyme Concentration Using Ultrafiltration
  15. Identification and Expression of an APETALA2 -Like Gene from Nelumbo nucifera
  16. Identification and Expression of an APETALA2 -Like Gene from Nelumbo nucifera
  17. Loops Adjacent to Catalytic Region and Molecular Stability of Man1312
  18. Optimisation of Batch Culture Conditions for Cell-Envelope-Associated Proteinase Production from Lactobacillus delbrueckii subsp. lactis ATCC® 7830™
  19. Prokaryotic Expression, Purification and Characterization of Aspergillus sulphureus β-Mannanase and Site-Directed Mutagenesis of the Catalytic Residues
  20. The Bioconversion of Pretreated Cashew Apple Bagasse into Ethanol by SHF and SSF Processes
  21. Biosorption of Heavy Metal Ions (Cu 2+ , Mn 2+ , Zn 2+ , and Fe 3+ ) from Aqueous Solutions Using Activated Sludge: Comparison of Aerobic Activated Sludge with Anaerobic Activated Sludge
  22. Improvement of Regio-Specific Production of Myricetin-3- O -α- l -Rhamnoside in Engineered Escherichia coli
  23. Purification of Alcohol Dehydrogenase from Saccharomyces cerevisiae Using Magnetic Dye-Ligand Affinity Nanostructures
  24. A Novel Hatching Enzyme from Starfish Asterias amurensis : Purification, Characterization, and Cleavage Specificity
  25. Purification, Sequencing, and Biochemical Characterization of a Novel Calcium-Independent α-Amylase AmyTVE from Thermoactinomyces vulgaris
  26. Purification, Sequencing, and Biochemical Characterization of a Novel Calcium-Independent α-Amylase AmyTVE from Thermoactinomyces vulgaris
  27. Improvement in the Purification Process of the Capsular Polysaccharide from Haemophilus influenzae Type b by Using Tangential Ultrafiltration and Diafiltration
  28. A Thermostable Alkaline Lipase from a Local Isolate Bacillus subtilis EH 37: Characterization, Partial Purification, and Application in Organic Synthesis
  29. Occurrence of Cellulose-Producing Gluconacetobacter spp. in Fruit Samples and Kombucha Tea, and Production of the Biopolymer
  30. The Application of the Biolog EcoPlate Approach in Ecotoxicological Evaluation of Dairy Sewage Sludge
  31. Enhanced Lipid Production by Co-cultivation and Co-encapsulation of Oleaginous Yeast Trichosporonoides spathulata with Microalgae in Alginate Gel Beads
  32. Stabilization of Chromobacterium viscosum Lipase (CVL) Against Ultrasound Inactivation by the Pretreatment with Polyethylene Glycol (PEG)
  33. Use of Swine Wastewater as Alternative Substrate for Mycelial Bioconversion of White Rot Fungi
  34. Collagen Hydrolysates of Skin Shavings Prepared by Enzymatic Hydrolysis as a Natural Flocculant and Their Flocculating Property
  35. Purification and Characterization of Pepsin-Solubilized Collagen from Skin of Sea Cucumber Holothuria parva
  36. Fractionation of Sugarcane Bagasse Using a Combined Process of Dilute Acid and Ionic Liquid Treatments
  37. Indigoids Biosynthesis from Indole by Two Phenol-Degrading Strains, Pseudomonas sp. PI1 and Acinetobacter sp. PI2
  38. Production and Properties of Two Novel Exopolysaccharides Synthesized by a Thermophilic Bacterium Aeribacillus pallidus 418
  39. Antifungal Activity of Diketopiperazines and Stilbenes Against Plant Pathogenic Fungi In Vitro
  40. Isolation, Purification and Characterisation of an Organic Solvent-Tolerant Ca 2+ -Dependent Protease from Bacillus megaterium AU02
  41. Simulated Microgravity Affects Growth of Escherichia coli and Recombinant β- d -Glucuronidase Production
  42. Immobilization of Candida antarctica Lipase B on Magnetic Poly(Urea-Urethane) Nanoparticles
  43. Gene Cloning, Overexpression, and Characterization of the Nitrilase from Rhodococcus rhodochrous tg1-A6 in E. coli
  44. Overview of Special Session B—Compositional and Structural Analysis of Biomass
  45. Comparative Secretome Analysis of Aspergillus niger , Trichoderma reesei, and Penicillium oxalicum During Solid-State Fermentation
  46. New Analytical Method using Coupled Enzymes for Determination of Polyunsaturated Fatty Acid Content in Olive Oil
  47. Serine Hydroxamate and the Transcriptome of High Cell Density Recombinant Escherichia coli MG1655
  48. Corn Fiber: Structure, Composition, and Response to Enzymes for Fermentable Sugars and Coproducts
  49. Enzymatic Hydrolysis of Polylactic Acid Fiber
  50. Specificity of Glucose Oxidase from Penicillium funiculosum 46.1 Towards Some Redox Mediators
  51. Kinetic Studies on the Product Inhibition of Enzymatic Lignocellulose Hydrolysis
  52. Partial Characterization of the Proteolytic Properties of an Enzymatic Extract From “Aguama” Bromelia pinguin L. Fruit Grown in Mexico
  53. Protease Production by Different Thermophilic Fungi
  54. Molecular Analysis of OsLEA4 and Its Contributions to Improve E. coli Viability
  55. Artificial Enzyme Mimics for Catalysis and Double Natural Enzyme Co-immobilization
  56. Genotypic Variability Among Soybean Genotypes Under NaCl Stress and Proteome Analysis of Salt-Tolerant Genotype
  57. Water Hyacinth as Carbon Source for the Production of Cellulase by Trichoderma reesei
  58. Graphene-Multiwall Carbon Nanotube-Gold Nanocluster Composites Modified Electrode for the Simultaneous Determination of Ascorbic Acid, Dopamine, and Uric Acid
  59. Expression and Characterization of a Recombinant Psychrophilic Cu/Zn Superoxide Dismutase from Deschampsia antarctica E. Desv. [Poaceae]
  60. Development and Characterization of an Environmentally Friendly Process Sequence (Autohydrolysis and Organosolv) for Wheat Straw Delignification
  61. A highly Conserved Aspartic Acid Residue of the Chitosanase from Bacillus Sp. TS Is Involved in the Substrate Binding
  62. Isolation and Immobilization of Influenza Virus-Specific N-SA-α-2,3-Gal Receptors Using Magnetic Nanoparticles Coated with Chitosan and Maackia amurensis Lectin
  63. Dynamics and Control Strategies for a Butanol Fermentation Process
  64. Effective Stimulation of the Biotechnological Potential of the Medicinal White Rot Fungus: Phellinus pini by Menadione-Mediated Oxidative Stress
  65. Metabolomics Approaches and Applications in Prostate Cancer Research
  66. Intraspecific Diversity within Ganoderma lucidum in the Production of Laccase and Mn-Oxidizing Peroxidases During Plant Residues Fermentation
  67. Investigation of Coculture of Human Adipose-Derived Stem Cells and Mature Adipocytes
  68. Antimicrobial and Antineoplasic Activity of Pleurotus ostreatus
  69. Naturally Occurring Alkaline Amino Acids Function as Efficient Catalysts on Knoevenagel Condensation at Physiological pH: A Mechanistic Elucidation
  70. Antibacterial and Antifungal Activity of Biopolymers Modified with Ionic Liquid and Laponite
  71. Modelling Growth and Bacteriocin Production by Pediococcus acidilactici PA003 as a Function of Temperature and pH Value
  72. Effects of Ascorbic Acid on PVS2 Cryopreservation of Dendrobium Bobby Messina’s PLBs Supported with SEM Analysis
  73. Use of Transgenic Oryzacystatin-I-Expressing Plants Enhances Recombinant Protein Production
  74. Synthesis of Pure meso -2,3-Butanediol from Crude Glycerol Using an Engineered Metabolic Pathway in Escherichia coli
  75. Single-step Purification and Immobilization of MBP–phytase Fusion on Starch Agar Beads: Application in Dephytination of Soy Milk
  76. Degradation of Polyurethane by Aspergillus flavus (ITCC 6051) Isolated from Soil
  77. Comparison of Yarrowia lipolytica Lipase Immobilization Yield of Entrapment, Adsorption, and Covalent Bond Techniques
  78. Bioconversion of Kraft Paper Mill Sludges to Ethanol by SSF and SSCF
  79. Heterologous Expression and Characterization of a Glycoside Hydrolase Family 45 endo -β-1,4-Glucanase from a Symbiotic Protist of the Lower Termite, Reticulitermes speratus
  80. Synthesis, Characterization, and DNA Binding Studies of a New Pt(II) Complex Containing the Drug Levetiracetam: Combining Experimental and Computational Methods
  81. Hydrolytic Methods for the Quantification of Fructose Equivalents in Herbaceous Biomass
Search Result: