Authors: Nasim Adibzadeh Saeed Aminzadeh Shahla Jamili Ali Asghar Karkhane Naser Farrokhi
Publish Date: 2014/03/28
Volume: 173, Issue: 1, Pages: 143-154
Abstract
Pepsinsolubilized collagen PSC was extracted from the skin of sea cucumber Holothuria parva and was fractionally characterized The PSC from H parva skin consisted of three α1 chains α13 in contrast to calf skin collagen type I with two α1 and one α2 chains α12α2 with approximately 130 kDa each The maximum transition Tm and denaturation temperature Td of PSC were determined to be 4694 and 325 °C respectively The amino acid composition analysis revealed that glycine proline alanine and hydroxyproline were the abundant amino acids available in extracted PSC The results showed that the isolated collagen from H parva has some similar characteristics to previously reported collagens used in food and pharmaceutical industries
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