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Title of Journal: Pediatr Nephrol

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Abbravation: Pediatric Nephrology

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Springer-Verlag

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DOI

10.1007/s11182-014-0228-4

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1432-198X

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Fungal peritonitis in children on peritoneal dialy

Authors: Renske Raaijmakers Cornelis Schröder Leo Monnens Elisabeth Cornelissen Adilla Warris
Publish Date: 2006/11/17
Volume: 22, Issue: 2, Pages: 288-293
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Abstract

Fungal peritonitis is a rare but serious complication in children on peritoneal dialysis PD In this study risk factors were evaluated and therapeutic measures were reviewed A retrospective multicentre study was performed in 159 Dutch paediatric PD patients between 1980 and 2005 3573 months All peritonitis episodes were reviewed Fungal peritonitis episodes were evaluated based on possible risk factors and treatment strategy A total of 321 episodes of peritonitis occurred with 9 cases of fungal peritonitis 29 Candida peritonitis occurred most frequently 78 Seven patients 78 had used antibiotics in the prior month Fungal peritonitis patients had a higher previous bacterial peritonitis rate compared to the total study population 013 versus 009 episodes/patientmonth with twice as many gram negative organisms In all fungal peritonitis patients the PD catheter was removed In four patients restart on PD was possible Fungal peritonitis is a rare complication of PD in children but is associated with high technique failure The most important risk factors are a high bacterial peritonitis rate prior use of antibiotics and previous bacterial peritonitis with gram negative organisms The PD catheter should be removed early but in children peritoneal lavage with fluconazole before removal may be useful to prevent technique failure

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