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Title of Journal: Pediatr Nephrol

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Abbravation: Pediatric Nephrology

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Springer-Verlag

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DOI

10.1002/9781119226574.app4

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1432-198X

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Oralibuprofeninduced acute renal failure in a pr

Authors: Omer Erdeve S Umit Sarici Erkan Sari Faysal Gok
Publish Date: 2008/04/30
Volume: 23, Issue: 9, Pages: 1565-1567
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Abstract

The side effects of indomethacin for ductal closure in preterm neonates eg increased incidence of necrotizing enterocolitis decreased cerebral blood volume and transient renal failure have led clinicians to seek a safer alternative Intravenous indomethacin and ibuprofen appear to be equally effective for patent ductus arteriosus closure but oral ibuprofen remains an experimental option with theoretical advantages yet with potential side effects We herein report a case of transient but severe acute renal failure developing in a preterm infant in whom oral ibuprofen was used and discuss the safety of this drug in relation to its pharmacokinetics

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  7. Roles of renal ammonia metabolism other than in acid–base homeostasis
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  18. Intravenous delivery of cysteamine for the treatment of cystinosis: association with hepatotoxicity
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  28. Hypertension and hemodialysis: pathophysiology and outcomes in adult and pediatric populations
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