Authors: Mark M Mitsnefes Chris Pierce Joseph Flynn Joshua Samuels Janis Dionne Susan Furth Bradley Warady For the CKiD study group
Publish Date: 2015/09/28
Volume: 31, Issue: 1, Pages: 163-166
Abstract
Studies in children with chronic kidney disease indicate a high prevalence of masked hypertension detected by ambulatory blood pressure monitoring ABPM However it is not well known if the frequency of masked hypertension is related to the level of normal casual blood pressure BPWe hypothesized that lower levels of normal casual BP are associated with a lower prevalence of masked hypertension Data from the chronic kidney disease CKiD cohort were analyzed crosssectionally across multiple visits The majority of children with normal casual BP also had normal wake and sleep ABP 60 even at the highest percentiles of casual BP The frequency of masked hypertension was lower in children with casual BP ≤25th percentile versus those with casual BP in 26–50th percentile and casual BP in 51–90th percentile during both wake and sleep periods In children with the lowest normal casual BP levels ≤25th percentile the frequency of abnormal mean wake or sleep ABP was 2–7 and of abnormal BP load was 6–16 Data in this manuscript were collected by the Chronic Kidney Disease in Children prospective cohort study CKiD The CKiD is funded by the National Institute of Diabetes and Digestive and Kidney Diseases with additional funding from the National Institute of Child Health and Human Development and the National Heart Lung and Blood Institute U01 DK82194 U01DK66143 U01DK66174 and U01DK66116 The CKID website is located at http//wwwstatepijhsphedu/ckid
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