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Title of Journal: Pediatr Nephrol

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Abbravation: Pediatric Nephrology

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Springer-Verlag

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DOI

10.1002/ejoc.201001710

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1432-198X

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The BK virus in renal transplant recipients—review

Authors: Vikas R Dharnidharka Husam A Abdulnour Carlos E Araya
Publish Date: 2010/12/15
Volume: 26, Issue: 10, Pages: 1763-1774
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Abstract

The BK virus a DNA virus from the Polyomavirus group represents an opportunistic infection of immunosuppressed transplant recipients Though the virus was discovered approximately 40 years ago the emergence of BK virus nephropathy since 1995 onwards with associated high graft loss rates has revolutionized renal transplantation medicine Kidney transplant professionals realized that the consequences of overimmunosuppression were as severe as the consequences of underimmunosuppression and we entered the era of immunosuppressive minimization Despite this recognition the optimal testing type for BK virus infections and frequency of testing are hotly debated Similarly optimal treatment strategies remain sources of intense controversy The authors review the current strategies of screening diagnosis and possible treatment and also review the amount and quality of evidence in favor or against Similarities and differences between cytomegalovirus EpsteinBarr virus and BV virus the three major viral infections in kidney transplantation are highlighted

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  1. Chronic kidney disease after liver, cardiac, lung, heart–lung, and hematopoietic stem cell transplant
  2. Abdominal pain in a female adolescent: answer
  3. Simvastatin ameliorates glomerulosclerosis in Adriamycin-induced-nephropathy rats
  4. Henoch-Schönlein purpura nephritis with nephrotic state in children: predictors of poor outcomes
  5. CFH gene mutation in a case of Shiga toxin-associated hemolytic uremic syndrome (STEC-HUS)
  6. Vincristine treatment in steroid-dependent nephrotic syndrome
  7. Roles of renal ammonia metabolism other than in acid–base homeostasis
  8. Catastrophic antiphospholipid antibody syndrome
  9. Congenital nephrotic syndrome with prolonged renal survival without renal replacement therapy
  10. Rhabdomyolysis: pathogenesis of renal injury and management
  11. Long-term outcome of children treated with rituximab for idiopathic nephrotic syndrome
  12. The clinical and laboratory features of Chinese Han anti-factor H autoantibody-associated hemolytic uremic syndrome
  13. Erratum to: Health-related quality of life and mental health in parents of children with hemolytic uremic syndrome
  14. Erratum to: Health-related quality of life and mental health in parents of children with hemolytic uremic syndrome
  15. Success of eculizumab in the treatment of atypical hemolytic uremic syndrome
  16. Fungal peritonitis in children on peritoneal dialysis
  17. A case of dense deposit disease associated with a group A streptococcal infection without the involvement of C3NeF or complement factor H deficiency
  18. Intravenous delivery of cysteamine for the treatment of cystinosis: association with hepatotoxicity
  19. An unusual cause of pleural effusion, urinothorax in a child with urinary stone disease
  20. Genetic polymorphisms and risk for acute renal failure in preterm neonates
  21. Outcome of dialysis in children with human immunodeficiency virus infection
  22. Outcome after renal transplantation. Part I: Intellectual and motor performance
  23. International validation of a urinary biomarker panel for identification of active lupus nephritis in children
  24. Macrovascular involvement in a child with atypical hemolytic uremic syndrome
  25. An infant presenting with a non-functional kidney on dimercaptosuccinic acid scan: question
  26. Maternal diabetes programs hypertension and kidney injury in offspring
  27. Nutritional management and growth in children with chronic kidney disease
  28. Hypertension and hemodialysis: pathophysiology and outcomes in adult and pediatric populations
  29. Age-related differences in Adriamycin-induced nephropathy
  30. Pattern of double glomerulopathy in children
  31. Growth after renal transplantation in infancy or early childhood
  32. Re-establishment of the ERA-EDTA Registry
  33. Primary hyperoxalurias: diagnosis and treatment
  34. Treatment of Wilms tumor-related hypertension with losartan and captopril
  35. NOx (nitrite/nitrate) in patients with pediatric nephrotic syndrome
  36. Vitamin D deficiency and parathyroid hormone levels following renal transplantation in children
  37. Circulating factor in FSGS: a black sheep in the suPAR family?
  38. Renin–angiotensin II–aldosterone system blockers and time to renal replacement therapy in children with CKD
  39. Factors affecting histological regression of crescentic Henoch–Schönlein nephritis in children
  40. The R229Q mutation in NPHS2 may predispose to proteinuria in thin-basement-membrane nephropathy
  41. Patterning and early cell lineage decisions in the developing kidney: the role of Pax genes
  42. Longitudinal growth in chronic hypokalemic disorders
  43. Sonic tooth brushing reduces gingival overgrowth in renal transplant recipients
  44. Is genetic testing of healthy pre-symptomatic children with possible Alport syndrome ethical?
  45. Genetic polymorphisms influence the steroid treatment of children with idiopathic nephrotic syndrome
  46. Severe neutropenia in children after renal transplantation: incidence, course, and treatment with granulocyte colony-stimulating factor
  47. Discrepancies in office and ambulatory blood pressure in adolescents: help or hindrance?
  48. Utility of fractional excretion of urea in the differential diagnosis of acute kidney injury in children
  49. Evaluation of certain constituents of antioxidant defense in youth treated in the past for steroid-sensitive idiopathic nephrotic syndrome
  50. Mizoribine for renal sarcoidosis: effective steroid tapering and prevention of recurrence
  51. The IL-6 −174G/C polymorphism and renal scarring in children with first acute pyelonephritis
  52. Neurological involvement in a child with atypical hemolytic uremic syndrome
  53. Unusual cause of anemia in a child with end-stage renal disease: Questions
  54. Uraemic vasculopathy in children with chronic kidney disease: prevention or damage limitation?
  55. Oral-ibuprofen-induced acute renal failure in a preterm infant
  56. Utility and cost of a renal transplant transition clinic
  57. Hyperuricemia and gout following pediatric renal transplantation
  58. Retinoic acid may increase the risk of bone marrow transplant nephropathy
  59. Vitamin E therapy in IgA nephropathy: a double-blind, placebo-controlled study
  60. Tissue factor pathway inhibitor in childhood nephrotic syndrome
  61. Sodium and potassium clearances by the maturing kidney: clinical-molecular correlates
  62. Atypical relapse of hemolytic uremic syndrome after transplantation
  63. Serum calcium values in term and late-preterm neonates receiving gentamicin
  64. Can office blood pressure readings predict masked hypertension?
  65. Searching the optimal PTH target range in children undergoing peritoneal dialysis: New insights from international cohort studies
  66. Anthropometric risk factors for elevated blood pressure in adolescents in Turkey aged 11–17
  67. High prevalence of elevated blood pressure among children with neurofibromatosis type 1
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  69. IgG subclasses and complement pathway in segmental and global membranous nephropathy
  70. Cinacalcet as adjunctive therapy in pseudohypoparathyroidism type 1b
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  72. Peritoneal–pericardial communication in an adolescent on peritoneal dialysis
  73. Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations
  74. Endothelial nitric oxide synthase gene intron 4 a/b VNTR polymorphism in children with APSGN
  75. Successful treatment of DEAP-HUS with eculizumab
  76. Crescentic glomerulonephritis in a child with infective endocarditis
  77. Early risk factors for neonatal mortality in CAKUT: analysis of 524 affected newborns
  78. Acute acalculous cholecystitis in a child with systemic lupus erythematosus
  79. Febrile urinary tract infection in children: ampicillin and trimethoprim insufficient as empirical mono-therapy
  80. Therapeutic strategies to slow chronic kidney disease progression
  81. WT1 and glomerular diseases
  82. Blood pressure control in pediatric hemodialysis: the Midwest Pediatric Nephrology Consortium Study
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  86. The use of darbepoetin in infants with chronic renal impairment
  87. Bone metabolism in oxalosis: a single-center study using new imaging techniques and biomarkers
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  89. The use of darbepoetin in infants with chronic renal impairment
  90. Maximizing the sensitivity of the indirect radionuclide cystogram: a retrospective audit
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