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Title of Journal: Pediatr Nephrol

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Abbravation: Pediatric Nephrology

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Springer-Verlag

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DOI

10.1016/0142-1123(82)90003-2

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1432-198X

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Growth after renal transplantation in infancy or e

Authors: E Qvist Eino Marttinen K Rönnholm Marjatta Antikainen Hannu Jalanko Ilkka Sipilä Christer Holmberg
Publish Date: 2014/03/08
Volume: 17, Issue: 6, Pages: 438-443
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Abstract

Fortyone children 5 years of age at kidney transplantation TX were investigated for growth bone age and renal function up to 7 years n=26 after TX All children received triple immunosuppression including alternateday corticosteroid treatment Catchup growth was seen in 81 of 30 children without growth hormone GH treatment Children 2 years of age without GH had a mean height standard deviation score hSDS of –11±08 at TX and –11±05 at 7 years children between 2 and 5 years improved their hSDS from –19±09 to –04±08 P00001 The hSDS at TX correlated inversely with the ΔhSDS from TX to 7 years r=–080 P=00002 Glomerular filtrations rate GFR at 5 years post TX correlated with the subsequent growth rate from 5 to 7 years TX r=058 P=001 Catchup growth was seen in all 11 children receiving GH Their mean hSDS improved from –25±09 to –11±09 P00001 In the majority of children receiving a kidney graft in early life triple immunosuppression with alternateday steroids can ensure catchup growth In children 5 years of age at TX growth is predicted better by the degree of stunting than by age

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