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Title of Journal: Pediatr Nephrol

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Abbravation: Pediatric Nephrology

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Springer-Verlag

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DOI

10.1002/nadc.19900380944

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1432-198X

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Outcome of dialysis in children with human immunod

Authors: Roberto Gordillo Juhi Kumar Marcela Del Rio Joseph T Flynn Robert P Woroniecki
Publish Date: 2008/09/23
Volume: 24, Issue: 1, Pages: 171-175
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Abstract

Human immunodeficiency virus HIV infection accounts for an unknown percentage of children with endstage kidney disease ESKD Our objective was to compare the outcome of renal replacement therapy RRT in subjects with ESKD due to HIV and other diagnoses and to examine the prevalence of ESKD due to HIV We analyzed Kt/V morbidity mortality echocardiography nutritional and transplant status in 12 dialysis patients with HIV and 32 without HIV followed at our center between February 2002 and February 2007 Body mass index BMI was lower and Kt/V higher in HIV than in nonHIV patients Shortening fraction was significantly lower in HIV patients There were six deaths in the HIV group and one in the nonHIV group over the study period Hemodialysis HD is the prevalent mode of RRT in HIV in urban settings and its adequacy as measured by Kt/V was higher in HIV patients than in nonHIV patients Decreased BMI and cardiovascular disease may be associated with increased mortality in children with HIV on RRT

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