Authors: Tom Dubov Hagit ToledanoAlhadef Gil Chernin Shlomi Constantini Roxana Cleper Shay BenShachar
Publish Date: 2015/08/28
Volume: 31, Issue: 1, Pages: 131-136
Abstract
Neurofibromatosis type 1 NF1 is a common neurocutaneous disease characterized by caféaulait spots axillary and inguinal freckling neurofibromas and optic gliomas Increased rates of hypertension HTN were reported among NF1 patients however the prevalence of HTN and preHTN in pediatric NF1 patients has not been clarifiedThe cohort’s mean age was 91 ± 41 years Overweight and obesity were found in 129 and 103 of them respectively BP was measured averagely 29 times per patient on different occasions Blood pressure was in the preHTN and HTN ranges in 149 and 169 of measurements respectively BP 95th was detected in 205 at the first measurement Of 114 children with at least three BP measurements 184 had two values in the HTN range and 614 had at least three Overweight was not associated with HTN among children with NF1 Urinary tract ultrasonographic abnormalities were detected in 68 11/161 of cases
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