Authors: Jutta Falger Bea Latal Markus A Landolt Phaedra Lehmann Thomas J Neuhaus Guido F Laube
Publish Date: 2008/04/04
Volume: 23, Issue: 8, Pages: 1339-1345
Abstract
Comprehensive information on neurodevelopmental outcome in children and adolescents with chronic kidney disease is still limited Intellectual performance IP and motor performance MP were systematically assessed in 27 patients at a median age of 141 years range 65–17 and 6 years range 05–127 after renal transplantation RTPL IP was analyzed with the Wechsler Intelligence Scale for ChildrenIII WISCIII in 25 patients and by the Kaufman Assessment Battery for Children in two patients MP was evaluated by the Zurich Neuromotor Assessment Median full scale intelligent quotient FSIQ was 97 range 49–133 Twentyone patients had an FSIQ ≥ 85 ie ≥ mean–1 standard deviation The five patients with neurological comorbidity had a median FSIQ of 81 range 49–101 Verbal IQ VIQ median 104 range 50–146 was significantly p 001 higher than performance IQ PIQ median 88 range 48–117 The PIQ was significantly lower compared with controls p 0007 and patients scored significantly lower compared with controls in five of 11 subtests of the Wechsler Scale All MP tasks were significantly p 001 lower than in controls and also in children without neurological comorbidity Socioeconomic status was significantly correlated with FSIQ p = 003 IP after RTPL was within the normal range for the majority of children PIQ was lower compared with VIQ and MP was significantly affected in all children after RTPL
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