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Title of Journal: Bull Exp Biol Med

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Abbravation: Bulletin of Experimental Biology and Medicine

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Publisher

Springer US

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DOI

10.1007/bf02255414

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ISSN

1573-8221

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Mechanisms of stimulation of granulocytopoiesis wi

Authors: T Yu Khrichkova V E Gol’dberg V V Zhdanov M G Matyash V V Vysotckaya E I Simolina V A Shatalova N O Popova L A Miroshnichenko A M Dygai
Publish Date: 2008/09/26
Volume: 145, Issue: 4, Pages: 467-471
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Abstract

The mechanisms of granulocytopoiesis stimulation with granulocytic CSF neupogen added to chemotherapy protocol adriablastine+taxotere in patients with stages III–IV breast cancer were studied The hemostimulatory effect of granulocytic CSF preparation is based on stimulation of proliferation and differentiation of granulomonocytopoisis precursor cell in the hemopoietic tissue due to neupogen effects on hemopoietic elements and on the hemopoiesisinducing microenvironment cells

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