Authors: A F Yakimovskii I I Stepanov
Publish Date: 2011/04/28
Volume: 150, Issue: 6, Pages: 665-
Abstract
The hyperkinekic effect increase in spontaneous activity and development of choreomyoclonic hyperkinesis of the extremities and body of picrotoxin injected into the rostral neostriatum of rats in a dose of 2 μg was reduced if the drug was injected together with ZnCl2 in a concentration of 01 μg/μl ZnCl2 in a concentration of 1 μg/μl did not modulate the effects of picrotoxin while in a concentration of 3 μg/μl it increased spontaneous motor activity in the open field test without affecting the symptoms of choreomyoclonic hyperkinesis
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