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Title of Journal: Bull Exp Biol Med

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Abbravation: Bulletin of Experimental Biology and Medicine

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Springer US

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DOI

10.1016/0300-9629(92)90040-W

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ISSN

1573-8221

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Neurogenesis Enhancer RO 256981 Facilitates Repea

Authors: O A Soloviova A T Proshin Z I Storozheva V V Sherstnev
Publish Date: 2012/10/20
Volume: 153, Issue: 5, Pages: 764-766
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Abstract

The effects of Ro 256981 selective NMDA receptor blocker in a dose stimulating neurogenesis on repeated learning reversal learning and memory reconsolidation were studied in adult rats in Morris water maze Ro 256981 facilitated repeated learning 13 days after injection but did not influence reversal learning The blocker injected directly before reminder did not disturb repeated learning and reversal learning in Morris water maze These effects of Ro 256981 on the dynamics of repeated learning seemed to be due to its effects on neurogenesis processes in adult brain

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