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Title of Journal: Bull Exp Biol Med

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Abbravation: Bulletin of Experimental Biology and Medicine

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Springer US

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DOI

10.1007/bf01339692

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ISSN

1573-8221

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AgeAssociated Characteristics of Vasomotor Regula

Authors: V M Chertok A E Kotsyuba
Publish Date: 2010/08/17
Volume: 149, Issue: 3, Pages: 364-368
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Abstract

The endotheliumdependent and myogenic reactions of pia mater arteries of the 1st5th branching orders were studied in 1 3 and 24monthold rats by biomicroscopy method The endotheliumindependent myogenic reaction predominated in the 1st3rd order branches and the endotheliumdependent vascular reaction in the 5th order branches of 3monthold rats Both regulatory mechanisms were equally developed in the 4th order branches In 1monthold rats the endotheliumdependent reaction was more active in the majority of branches In 24monthold rats this reaction was significantly higher than the endotheliumindependent one only in the 4th and 5th order branches In contrast to 3monthold rats the myogenic reaction of 24monthold animals predominated in the 1st and 2nd order branches and the endotheliumdependent one in the 4th and 5th order branches Vascular reactivity of 24monthold rats was lower than in younger rats in all cases

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