Authors: M A Bakarev A I Neimark E L Lushnikova A K Pichigina A V Yakovlev
Publish Date: 2015/11/25
Volume: 160, Issue: 1, Pages: 103-108
Abstract
Combinations of various factors of polypogenesis determine the formation of a mixed structural phenotype of urethral polyps consisting of heterogeneous changes of the epithelium hyperplasia metaplasia and erosions inflammatory cell infiltration of the stroma and dilatation of the venous plexus vessels Urogenital infections are associated with the predominance of symptoms of inflammation high serum levels of IL1β and TNFα more extensive areas of inflammatory infiltration and subepithelial microvascular bed predominance of hyperemic form of microcirculatory disorders The combination of hyperplastic reactions of the epithelial layer with neoangiogenesis and myofibroblast proliferation in the subepithelial zone confirms the key role of dysregeneratory hyperplasia in the mechanisms of polypogenesis
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