Authors: A I Volodchenko V I Tsirkin
Publish Date: 2014/09/27
Volume: 157, Issue: 5, Pages: 592-596
Abstract
We studied the effects of analogues of endogenous sensitizer of βadrenergic receptors histidine 10–4 g/ml and mildronate 10–5 g/ml and endogenous βadrenoreceptor blocker propranolol 10–6 g/ml on adrenoreactivity of erythrocytes in men assessed by changes in the rate of erythrocyte agglutination under the infl uence of epinephrine 10–1010–6 g/ml Epinephrine increased the rate of agglutination which attested to predominance of α1adrenoceptors Propranolol enhanced the effect of epinephrine while histidine and mildronate reduced it Hence endogenous modulators of adrenoceptors can modify adrenoreactivity of erythrocytes and probably other cells and erythrocytes can serve as indicator of instant adrenoreactivity of body cells
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