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Title of Journal: Diabetologia

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Abbravation: Diabetologia

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Springer-Verlag

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DOI

10.1007/s10856-006-0014-0

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1432-0428

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To BiasonLauber A Boehm B LangMuritano M et a

Authors: A D Paterson
Publish Date: 2005/08/13
Volume: 48, Issue: 10, Pages: 2179-2179
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Abstract

First the χ 2 tests provided for association of genotype with type 1 diabetes are incorrect I have recalculated them based on converting the genotype proportions into counts and have analysed them using PROC FREQ in SAS Version 91 for Windows Cary NC USA The correct values and df are as follows Swiss sample χ 2=149 2 df p00001 German sample χ 2=75 2 df p00001Of greatest concern is that the case and control groups for both the Swiss and German study populations deviate significantly from Hardy–Weinberg equilibrium Swiss cases p00005 Swiss control subjects p00001 German cases p005 German control subjects p00001 No Hardy–Weinberg calculations were presented in the paper In the Subjects and methods it is indicated that two different genotyping methods were used to generate the data but it was not stated which individuals were genotyped by which methodsFinally the relative risk calculation for the C/C genotype compared with the other genotypes footnote a to Table 1 is incorrect if it is calculated for either the combined Swiss and German samples or the individual samples The correct analysis for the combined Swiss and German samples produces an odds ratio of 61 95 CI 47–79

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  2. Glycated albumin but not HbA 1c reflects glycaemic control in patients with neonatal diabetes mellitus
  3. Comparison of high-fat and high-protein diets with a high-carbohydrate diet in insulin-resistant obese women
  4. Lack of association between gene variants in the ALMS1 gene and Type 2 diabetes mellitus
  5. Lack of association between gene variants in the ALMS1 gene and Type 2 diabetes mellitus
  6. Low-density-lipoprotein cholesterol concentrations and risk of incident diabetes: epidemiological and genetic insights from the Framingham Heart Study
  7. AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice
  8. Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study
  9. Angiotensin-I converting enzyme insertion/deletion polymorphism and its association with diabetic nephropathy: a meta-analysis of studies reported between 1994 and 2004 and comprising 14,727 subjects
  10. Microarray analysis of genes with impaired insulin regulation in the skeletal muscle of type 2 diabetic patients indicates the involvement of basic helix-loop-helix domain-containing, class B, 2 protein (BHLHB2)
  11. Amino acids require glucose to enhance, through phosphoinositide-dependent protein kinase 1, the insulin-activated protein kinase B cascade in insulin-resistant rat adipocytes
  12. Prevalence and 25 year incidence of proliferative retinopathy among Danish type 1 diabetic patients
  13. Prevalence and 25 year incidence of proliferative retinopathy among Danish type 1 diabetic patients
  14. Retinol-binding protein 4 is associated with components of the metabolic syndrome, but not with insulin resistance, in men with type 2 diabetes or coronary artery disease
  15. Effects of exenatide on circulating glucose, insulin, glucagon, cortisol and catecholamines in healthy volunteers during exercise
  16. Genome-wide scans for heritability of fasting serum insulin and glucose concentrations in hypertensive families
  17. Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour
  18. Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat
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  20. Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study
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  24. Glucose tolerance and insulin resistance in Indian children: relationship to infant feeding pattern
  25. The response of serum glucose, free fatty acid and immunoreactive insulin to oral glucose and intravenous tolbutamide in normal, potentially diabetic and diabetic subjects
  26. An RBP4 promoter polymorphism increases risk of type 2 diabetes
  27. Müller glial dysfunction during diabetic retinopathy in rats is linked to accumulation of advanced glycation end-products and advanced lipoxidation end-products
  28. WNT/β-catenin increases the production of incretins by entero-endocrine cells
  29. Enhanced susceptibility of Cpt1c knockout mice to glucose intolerance induced by a high-fat diet involves elevated hepatic gluconeogenesis and decreased skeletal muscle glucose uptake
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  50. Harry Keen, 1925–2013
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  53. R. Tattersall. Diabetes: the biography. Oxford University Press, Oxford, 2009
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