Authors: Meenakshi Garg Pranav Mehra Devi Dayal Bansal
Publish Date: 2014/01/05
Volume: 389, Issue: 1-2, Pages: 35-41
Abstract
This study was designed to determine chronic effect of high sucrose low magnesium HSLM diet in weanling rats on plasma thyroid profile catecholamines and activities of key hepatic glycolytic and gluconeogenic enzymes Compared to control diet fed group significantly elevated levels of plasma triiodothyronine tetraiodothyronine catecholamines epinephrine norepinephrine and dopamine and activity of hepatic glycolytic hexokinase and glucokinase and gluconeogenic glucose6phosphatase enzymes were observed in high sucrose and low magnesium fed groups However HSLM diet had an additive effect on all these three parameters The study thus assumes significance as it shows that hormonal imbalance and disorders in carbohydrate metabolism at an early stage of development can be due to dietary modification or due to deficiency of key element magnesium
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