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Title of Journal: Eur Radiol

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Abbravation: European Radiology

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Springer-Verlag

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DOI

10.1002/adsc.201000670

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1432-1084

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Diffusion MRI and spectroscopy in Rasmussens ence

Authors: R N Sener
Publish Date: 2002/09/11
Volume: 13, Issue: 9, Pages: 2186-2191
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Abstract

The purpose of this study was to evaluate the diffusion MRI and proton MR spectroscopy findings in a rare disorder Rasmussens encephalitis Diffusion MRI studies of 3 cases of Rasmussens encephalitis were performed using the echoplanar trace sequence TR=5700 ms TE=13903 ms The gradientecho diffusion sequence PSIF TR=216 ms TE=5 ms which is a reverse FISP sequence and proton MR spectroscopy TR=1500 ms TE=40 ms were applied in two patients The trace sequence revealed high apparent diffusion coefficient values at the diseased regions 121±013×10–3 mm2/s compared with normal parenchymal values in 12 control cases 084±009×10–3 mm2/s indicating increased motion of water molecules disintegration of the tissue in these regions The PSIF sequence revealed pixel value differences between the two hemispheres Proton MR spectroscopy revealed decreased Nacetyl aspartate peaks compared with five control cases

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