Authors: Eyal Klang Noa Rozendorn Steve Raskin Orith Portnoy Miri Sklair Edith M Marom Eli Konen Michal M Amitai
Publish Date: 2016/05/26
Volume: 27, Issue: 2, Pages: 536-542
Abstract
Ninetyfour patients with pretreatment CT scan and markers bhCG AFP LDH were retrospectively collected A radiologist measured diameters in all CT examinations and correlation between diameters and log bhCG was assessed Pearson’s coefficient The ability of measured diameters to predict lymphatic and distant haematogenous metastatic spread was evaluated ROC curves The associations between measured diameter cutoff values of 20 and 25 mm and International Germ Cell Cancer Collaborative Group IGCCCG classification lymphatic and distant haematogenous metastatic spread and histological subtypes were evaluated chi squared testBreast glandular diameters correlated to logbhCG r = 0579 and predicted distant haematogenous metastatic spread AUC = 078 Worse prognosis intermediate or poor IGCCCG was shown for 20 mm 273 vs 42 p = 0005 and 25 mm 333 vs 61 p = 0014 A diameter of 25 mm was associated with nonseminoma 917 vs 488 p = 0005The scientific guarantor of this publication is Dr Eyal Klang The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article The authors state that this work has not received any funding One of the authors has significant statistical expertise Institutional Review Board approval was obtained Written informed consent was waived by the Institutional Review Board An abstract of this paper was orally presented at the Israeli radiological convention Methodology retrospective crosssectional study performed at one institution
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