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Title of Journal: Eur Radiol

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Abbravation: European Radiology

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Springer-Verlag

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DOI

10.1006/qres.1999.2126

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1432-1084

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MR imaging of renal cortical tumours qualitative

Authors: Christoph A Karlo Olivio F Donati Irene A Burger Junting Zheng Chaya S Moskowitz Hedvig Hricak Oguz Akin
Publish Date: 2013/01/10
Volume: 23, Issue: 6, Pages: 1738-1744
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Abstract

A total of 251 consecutive patients underwent 15T MRI before nephrectomy Two readers R1 R2 independently evaluated all tumours visually for a decrease in signal intensity SI on opposed compared with inphase chemical shift images In addition SI was measured on in and opposedphase images SIIP SIOP and the chemical shift index was calculated as a measure of percentage SI change Histopathology served as the standard of referenceA visual decrease in SI was identified significantly more often in clear cell renal cell carcinoma RCCs R1 73  R2 64  and angiomyolipomas both 80  than in oncocytomas 29  12  papillary 29  17  and chromophobe RCCs 13  9  all P  005 Median chemical shift index was significantly greater in clear cell RCC and angiomyolipoma than in the other histological subtypes both P  0001 Interobserver agreement was fair for visual kappa 04 and excellent for quantitative analysis concordance correlation coefficient 080A decrease in SI on opposedphase chemical shift images is not an identifying feature of clear cell RCCs or angiomyolipomas but can also be observed in oncocytomas papillary and chromophobe RCCs After excluding angiomyolipomas a decrease in SI of more than 25  was diagnostic for clear cell RCCs

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