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Title of Journal: Eur Radiol

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Abbravation: European Radiology

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Springer Berlin Heidelberg

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DOI

10.1007/bf00175218

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1432-1084

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Incidence of bowel wall oedema on computed tomogra

Authors: Liesbeth Cornelissen Filip Claus Pascal Wolter Herlinde Dumez Frederik De Keyzer Evelyne Lerut Hendrik Van Poppel Benoit Beuselinck
Publish Date: 2014/08/28
Volume: 25, Issue: 2, Pages: 375-379
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Abstract

We conducted a retrospective analysis of all RCC patients treated with sunitinib at our hospital between December 2005 and December 2011 The presence or absence of bowel wall oedema on these CT examinations was scored The presence of diarrhoea preceding during or after sunitinib treatment was identified from the patient files and retrospectively gradedFor 54 of 87 patients bowel wall oedema was present on at least one CT examination Of these 54 patients the rightsided colonic segment was affected in 87  Diarrhoea was the most common reported adverse event during treatment with 58 patients 67  having grade 1/2 diarrhoea and 9 patients 10  having grade 3 There was a statistically significant correlation between the incidence of CTscored bowel oedema and diarrhoea during sunitinib treatment P = 0004

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