Authors: Nam Kyung Lee Suk Kim Hyung Il Seo Dong Uk Kim Hyun Young Woo Tae Un Kim
Publish Date: 2012/12/07
Volume: 23, Issue: 5, Pages: 1288-1296
Abstract
We retrospectively analysed data from 78 patients who had undergone magnetic resonance cholangiopanreatography MRCP and diffusionweighted imaging DWI in whom biliary strictures in the periampullary region were suspected Twentytwo malignant and 56 benign lesions were included One radiologist compared the signal intensity of malignant and benign periampullary lesions on DWI using b = 500 and 800 s/mm2 The signal intensity of bile was also compared and an optimal b value was determined for periampullary lesions Two other radiologists reviewed MRCP alone and combined DWI and MRCP for the possibility of malignant periampullary lesions Diagnostic accuracy was calculated for each reviewer by receiver operating characteristic ROC curve analysisMalignant periampullary lesions more frequently appeared hyperintense than benign lesions on DWI using the two b values P 0001 Bile more frequently appeared hyperintense on DWI using b = 500 s/mm2 872 than b = 800 s/mm2 244 Therefore b = 800 s/mm2 was determined as the preferred sequence Diagnostic accuracy for malignant periampullary lesions improved for both reviewers after adding DWI from 0714 to 0924 P = 0006 for reviewer 1 and from 0714 to 0919 P = 0007 reviewer 2
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