Authors: Maram M Alakhras Patrick C Brennan Mary Rickard Roger Bourne Claudia MelloThoms
Publish Date: 2014/09/06
Volume: 25, Issue: 2, Pages: 402-409
Abstract
Ethical committee approval was obtained Fifty cases 27 cancer 23 normal each containing both digital mammography DM and digital breast tomosynthesis DBT images were reviewed by 26 radiologists divided into three groups according to level of experience with DBT none workshop experience and clinical experience The radiologists’ diagnostic performance using DM was compared with that using DM + DBT and evaluated by area under receiveroperating characteristic curve AUC jackknife freeresponse receiveroperator characteristics figure of metric JAFROC FOM sensitivity location sensitivity and specificityFor all readers combined performance using DM + DBT was significantly higher than for DM alone by both AUC 0788 vs 0681 p 0001 and JAFROC FOM 0745 vs 0621 p 0001 Similar results were obtained for readers with no DBT experience AUC 0775 vs 0682 p = 0004 JAFROC FOM 0695 vs 0603 p = 0016 and with clinical DBT experience AUC 0789 vs 0681 p = 0042 and JAFROC FOM 0764 vs 0632 p = 0031The authors gratefully acknowledge the generous funding support provided by Australia’s National Breast Cancer Foundation under the Novel Concept Award Scheme The authors thank Sydney Breast Clinic for providing the images Hologic for their efforts in setting up the workstations and Jordan University of Science and Technology for their sponsorshipThe scientific guarantor of this publication is Maram Mustafa Alakhras No complex statistical methods were necessary for this paper Institutional Review Board approval was obtained Written informed consent was obtained from all subjects patients in this study Methodology Retrospective Diagnostic study Performed at one institution
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