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Title of Journal: Dig Dis Sci

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Abbravation: Digestive Diseases and Sciences

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Springer US

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DOI

10.1016/0016-5085(94)90272-0

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ISSN

1573-2568

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Marked Decrease of Serum Ca 125 Levels After Denve

Authors: L Leggio L Abenavoli C D’Angelo A Ferrulli L Vonghia A Mirijello R Barbarino T De Michele C Zuppi D Gui G L Rapaccini G Gasbarrini G Addolorato
Publish Date: 2006/08/22
Volume: 51, Issue: 9, Pages: 1644-1646
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Abstract

Increased serum CA 125 levels can be associated with chronic liver disease and particularly with liver cirrhosis 1 2 3 4 In addition a relationship has recently been described between CA 125 and the amount of ascites 5 and a significant decrease of CA 125 after largevolume paracentesis 5 or liver transplantation 6 in patients with decompensated cirrhosisHowever in reviewing the English literature we found no reports or studies showing the course of serum CA 125 levels after the placement of a peritoneovenous surgical shunt We report a case of a marked decrease of high serum CA 125 levels after Denver shunt placement in a patient with liver cirrhosis complicated by refractory ascitesA 51yearold Caucasian man affected by alcoholrelated liver cirrhosis ChildPugh score 12 was admitted to our hospital for refractory ascites the patient presented a slight encephalopathy Table 1 and esophageal varices with a low risk of bleeding

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