Authors: Jonah N Rubin Helen S Te
Publish Date: 2016/01/02
Volume: 61, Issue: 6, Pages: 1757-1762
Abstract
Autoimmune hepatitis AIH can be difficult to control particularly in some AfricanAmericans When standard therapy of prednisone and azathioprine is ineffective or poorly tolerated alternative therapies are resorted to We report two patients with AIH who were refractory to or intolerant of standard therapy They initially responded to a combination of tacrolimus and MMF but eventually developed acute flares of the disease that had to be managed with sirolimus and in one case rituximab to achieve remission
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