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Title of Journal: Dig Dis Sci

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Abbravation: Digestive Diseases and Sciences

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Springer US

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DOI

10.1007/bf02446295

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ISSN

1573-2568

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Factors Predictive of Adverse Events Following End

Authors: Soo Jung Park Jin Hong Kim Jae Chul Hwang Ho Gak Kim Don Haeng Lee Seok Jeong SangWoo Cha Young Deok Cho Hong Ja Kim Jong Hyeok Kim Jong Ho Moon SangHeum Park Takao Itoi Hiroyuki Isayama Hirofumi Kogure Se Joon Lee Kyo Tae Jung Hye Sun Lee Todd H Baron Dong Ki Lee
Publish Date: 2012/12/08
Volume: 58, Issue: 4, Pages: 1100-1109
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Abstract

This multicenter retrospective study investigated 946 consecutive patients who underwent attempted removal of CBD stones ≥10 mm in size using EPLBD balloon size 12–20 mm with or without endoscopic sphincterotomy EST at 12 academic medical centers in Korea and JapanNinetyfive 100  patients exhibited AEs including bleeding in 56 pancreatitis in 24 perforation in nine and cholangitis in six 90 947  of these were classified as mild or moderate in severity There were four deaths three as a result of perforation and one due to delayed massive bleeding Causative factors identified in fatal cases were fullEST and continued balloon inflation despite a persistent waist seen fluoroscopically Multivariate analyses showed that cirrhosis OR 803 p = 0003 length of EST fullEST OR 622 p  0001 and stone size ≥16 mm OR 400 p  0001 were associated with increased bleeding and distal CBD stricture OR 1708 p  0001 was an independent predictor for perforation On the other hand balloon size was associated with deceased pancreatitis ≥14 mm OR 027 p = 0015

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