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Title of Journal: Arch Virol

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Abbravation: Archives of Virology

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Springer Vienna

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DOI

10.1002/smj.565

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ISSN

1432-8798

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An investigation into the use of human papillomavi

Authors: Oliver P Windram Brandon Weber Mohamed A Jaffer Edward P Rybicki Dionne N Shepherd Arvind Varsani
Publish Date: 2008/01/04
Volume: 153, Issue: 3, Pages: 585-589
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Abstract

Development of vaccine strategies against human papillomavirus HPV which causes cervical cancer is a priority We investigated the use of viruslike particles VLPs of the most prevalent type HPV16 as carriers of foreign proteins Green fluorescent protein GFP was fused to the N or C terminus of both L1 and L2 with L2 chimeras being coexpressed with native L1 Purified chimaeric VLPs were comparable in size ∼55 nm to native HPV VLPs Conformationspecific monoclonal antibodies Mabs bound to the VLPs thereby indicating that they possibly retain their antigenicity In addition all of the VLPs encapsidated DNA in the range of 6–8 kbWe would like thank to Dr Neil Christensen for providing the monoclonal antibodies used in this study This research was funded by the Poliomyelitis Research Foundation of South Africa grant 04/25 and the University of Cape Town start up grant AV is supported by the Carnegie Corporation of New York

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  3. High-temperature-mediated spontaneous mutations in the coat protein of cucumber mosaic virus in Nicotiana tabacum
  4. Engineered retroviral virus-like particles for receptor targeting
  5. Complete nucleotide sequence of rose yellow vein virus, a member of the family Caulimoviridae having a novel genome organization
  6. Capulavirus and Grablovirus : two new genera in the family Geminiviridae
  7. Immunoelectron microscopy analysis of HCMV gpUL73 (gN) localization
  8. Infectious bursal disease virus polyprotein expression arrests growth and mitogenic stimulation of B lymphocytes
  9. Association of lipid profile alterations with severe forms of dengue in humans
  10. Molecular detection and genome characterization of porcine circovirus type 2 in rats captured on commercial swine farms
  11. Sequence analysis of the CXCR4 gene derived from cells surviving feline lentivirus infection
  12. Expression of porcine Mx1 with FMDV IRES enhances the antiviral activity against foot-and-mouth disease virus in PK-15 cells
  13. Identification of amino acid residues of Ljungan virus VP0 and VP1 associated with cytolytic replication in cultured cells
  14. Comparison of the coat protein genes of Lettuce big - vein associated virus isolates from Australia with those of isolates from other continents
  15. Nitric oxide inhibits the replication cycle of porcine parvovirus in vitro
  16. Isolation of a cytopathogenic virus from a case of porcine reproductive and respiratory syndrome (PRRS) and its characterization as parainfluenza virus type 2
  17. Eukaryotic elongation factor 1-beta interacts with the 5′ untranslated region of the M gene of Nipah virus to promote mRNA translation
  18. An overview of infectious bursal disease
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  20. Molecular characterisation of wild-type G1P[8] and G3P[8] rotaviruses isolated in Vietnam 2008 during a vaccine trial
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  27. Profile of drug resistance mutations among HIV-1-infected Tunisian subjects failing antiretroviral therapy
  28. Complete genome sequence analysis of Japanese encephalitis virus isolated from a horse in India
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  30. Characteristics of two highly pathogenic avian influenza H5N8 viruses with different pathogenicity in mice
  31. Molecular characterization of a canine coronavirus NA/09 strain detected in a dog’s organs
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  48. The influence of the milieu on the rate of neutralisation of herpes simplex virus 1
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  50. Neutralization of animal virus infectivity by antibody
  51. Peanut stunt virus 2b cistron plays a role in viral local and systemic accumulation and virulence in Nicotiana benthamiana
  52. Antiviral activity of recombinant porcine surfactant protein A against porcine reproductive and respiratory syndrome virus in vitro
  53. Molecular diversity of tobacco vein banding mosaic virus
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  55. Pregnancy outcome and clinical status of gilts following experimental infection by H1N2, H3N2 and H1N1pdm09 influenza A viruses during the last month of gestation
  56. Identification of bacteriophage types and their carriage in Staphylococcus aureus
  57. CPm gene diversity in field isolates of Citrus tristeza virus from Colombia
  58. Primary mouse dermal fibroblast cell cultures as an in vitro model system for the differential pathogenicity of cross-species herpesvirus papio 2 infections
  59. Identification of a recombinant dengue virus type 1 with 3 recombination regions in natural populations in Guangdong province, China
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  61. Molecular characterization of a Hungarian isolate of Tobacco necrosis virus A
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