Authors: Hebata Allah Mahgoub
Publish Date: 2012/06/17
Volume: 157, Issue: 11, Pages: 2047-2057
Abstract
Infectious bursal disease IBD is a viral immunosuppressive disease of chickens attacking mainly an important lymphoid organ in birds the bursa of Fabricius BF The emergence of new variant strains of the causative agent infectious bursal disease virus IBDV has made it more urgent to develop new vaccination strategies against IBD One of these strategies is the use of recombinant vaccines DNA and viralvectored vaccines Several studies have investigated the host immune response towards IBDV This review will present a detailed background on the disease and its causative agent accompanied by a summary of the most recent findings regarding the host immune response to IBDV infection and the use of recombinant vaccines against IBD
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