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Title of Journal: Inflammation

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Abbravation: Inflammation

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Springer US

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DOI

10.1016/0031-9163(65)90381-1

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1573-2576

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Pentraxin 3 Values During Normal Pregnancy

Authors: Anders Larsson Maria Palm Johanna Helmersson Ove Axelsson
Publish Date: 2010/09/18
Volume: 34, Issue: 5, Pages: 448-451
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Abstract

Pentraxin 3 PTX3 is an inflammatory molecule that has been reported to be a promising early biomarker for subsequent preeclampsia The levels of PTX3 vary during pregnancy and it is thus a need to establish reference intervals during normal pregnancy Repeated blood samples were collected from 52 healthy pregnant females The samples were divided according to collection time into the following groups week 7–17 week 17–24 week 24–28 week 28–31 week 31–34 week 34–38 before delivery and after delivery The samples were analyzed for PTX3 with a sandwich ELISA and the 25 and 975 percentiles for each sample period was calculated There was a continuous increase of serum PTX3 as pregnancy progressed The increase was most evident after week 31 with the highest levels just before delivery

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