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Title of Journal: Inflammation

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Abbravation: Inflammation

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Springer US

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DOI

10.1002/mdc3.12165

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1573-2576

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Role of Antiinflammatory Cytokines IL35 and IL3

Authors: Daiju Hu
Publish Date: 2016/11/23
Volume: 40, Issue: 2, Pages: 697-707
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Abstract

Asthma is a chronic airway inflammation that is characterized by intense eosinophil infiltrates mucus hypersecretion airway remodeling and airway hyperresponsiveness Interleukin IL35 and IL37 are two cytokines with antiinflammatory effects found in immune response Recent findings suggested that expressions of IL35 and IL37 are abnormal in asthma Functional analysis further confirmed the important roles of them in the pathogenesis of asthma The present study reviewed the updated evidence indicating the roles of IL35 and IL37 in asthma Hopefully the information obtained may lead to a better understanding of the pathogenesis of the disease

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