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Title of Journal: Mol Biol Rep

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Abbravation: Molecular Biology Reports

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Springer Netherlands

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DOI

10.1007/s11253-014-0913-z

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ISSN

1573-4978

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Molecular cloning expression patterns and subcell

Authors: Zhisheng Zhang Delin Mo Peiqing Cong Zuyong He Fei Ling Anning Li Yuna Niu Xiao Zhao Chunyan Zhou Yaosheng Chen
Publish Date: 2009/05/16
Volume: 37, Issue: 3, Pages: 1611-1618
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Abstract

The product of transmembrane and coiledcoil domains 1 TMCO1 gene is a member of DUF841 superfamily of several eukaryotic proteins with unknown function The partial DNA sequence of porcine TMCO1 was first cloned with a pig 567 bp ORF encoding 188 amino acids By tissues expression analysis the TMCO1 was found highly expressed in the liver kidney and heart The porcine TMCO1 protein was subsequently demonstrated to localize in the mitochondrion by confocal fluorescence microscopy This data provides an important basis for conducing further studies on the functions and regulatory mechanisms underlying the role of TMCO1 gene

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