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Title of Journal: Mol Biol Rep

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Abbravation: Molecular Biology Reports

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Springer Netherlands

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ISSN

1573-4978

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Luteolin suppresses growth and migration of human

Authors: Yunxue Zhao Guotao Yang Dongmei Ren Xiumei Zhang Qiuwei Yin Xuefei Sun
Publish Date: 2010/06/30
Volume: 38, Issue: 2, Pages: 1115-1119
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Abstract

Luteolin 3′4′57tetrahydroxyflavone has been shown to possess antioxidant antiinflammation and anticancer properties However its role in lung cancer remains poorly understood Here we examined the antitumorigenic role of luteolin in a commonly used lung cancer cell line Luteolin inhibited the growth of A549 cells by inducing G1 phase cell cycle arrest and apoptosis Furthermore stress fiber assembly and cell migration in A549 cells was markedly suppressed by luteolin

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