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Title of Journal: Anal Bioanal Chem

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Abbravation: Analytical and Bioanalytical Chemistry

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Springer-Verlag

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DOI

10.1016/0369-643x(57)90031-2

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1618-2650

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From fundamentals to applications recent developm

Authors: Suzanne J Bos Suze M van Leeuwen Uwe Karst
Publish Date: 2005/09/02
Volume: 384, Issue: 1, Pages: 85-
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Abstract

Only five years after the first publication on atmospheric pressure photoionization APPI this technique has evolved rapidly as a very useful complement to established ionization techniques for liquid chromatography/mass spectrometry LC/MS This is reflected in a rapidly increasing number of publications in this field On the one hand thorough studies into the photoionization mechanism have provided deep insights into the roles and influences of the solvent the dopant and other additives On the other hand a large number of new and attractive applications have recently been introduced New instrumental developments have resulted in combined APPI/ESI PAESI and APPI/APCI sources and a microfabricated APPI source In this review the most important developments within the field are summarized focusing in particular on the applications of the technique

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