Authors: Linzhi Tang Nae Yoon Lee
Publish Date: 2009/04/18
Volume: 394, Issue: 4, Pages: 1227-1232
Abstract
Herein we introduce the fabrication of a microperforated elastomeric polydimethylsiloxane PDMS mask and employ it for spatially defined surface modification To fabricate the microperforated PDMS mask highaspectratio micropillar arrays having millimeter scale height were first fabricated via direct photopolymerization using a thiol–enebased UVcurable adhesive Square pillars 500 × 500 µm and 200 µm circular pillars with 5 and 125 in the aspect ratios respectively were successfully fabricated with high pattern fidelity reaching 25mm in height Next using the micropillararray platform as a master mold PDMS prepolymer was cast and polymerized to form an elastomeric PDMS mask having microperforation arrays Alternating hydrophilic and hydrophobic surfaces were successfully obtained by oxidizing PDMScovered Si wafer with corona discharge Spatially defined chemical functionalities obtained by selective oxidation and subsequent silanization were clearly distinguished via colorimetric detection methods employing ninhydrin and toluidine reagents The microperforated elastomeric PDMS mask enables selective modification of a surface without utilizing photoreactive chemicals and a photomaskThis work was supported by the Korea Research Foundation Grant funded by the Korean Government MOEHRD KRF2008531D00002 This work was also partly supported by the GRRC program of Gyeonggi province 20080167 Development of microfluidic devices for the diagnosis of disease the Korea Science and Engineering Foundation KOSEF grant funded by the Korea government MOST No M1075516000207N551600210 and the Kyungwon University Research Fund in 2007
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