Authors: Jiadi Sun Jian Ji Yifan Wang Ying Zhao Yinzhi Zhang Xiulan Sun
Publish Date: 2015/01/11
Volume: 407, Issue: 7, Pages: 1951-1959
Abstract
A novel tulathromycin TLTMC electrochemical sensor based on molecularly imprinted polymer MIP membranes was constructed pAminothiophenol pATP and TLTMC were assembled on the surface of gold nanoparticles AuNPs modified on the gold electrode GE by the formation of AuS bonds and hydrogenbonding interactions Besides polymer membranes were formed by electropolymerization in a polymer solution containing pATP tetrachloroaurateIII acid HAuCl4 tetrabutylammonium perchlorate TBAP and a template molecule TLTMC A novel molecular imprinted sensor MIS in this experiment was achieved after the removal of TLTMC Cyclic voltammetry CV and differential pulse voltammetry DPV measurements were used to illustrate the process of electropolymerization and its optimal conditions The electrode with MIP obtained the linear of response range which was between 30 × 10–12 mol L–1 and 70 × 10–9 mol L–1 and the limit of detection was 10 × 10–12 mol L–1 All the obtained results indicate that the MIS tends to be an effective electrochemical technique for the determination of TLTMC in realtime and in a complicated matrixThis work was supported by the National Natural Science Foundation of China no 31371768 Key Laboratory of Industrial Biotechnology Ministry of EducationKLIBKF201109 Program for New Century Excellent Talents in Jiangnan University and Priority Academic Program Development of Jiangsu Higher Education Institutions
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