Authors: Anna Nordborg Emily F Hilder
Publish Date: 2009/02/11
Volume: 394, Issue: 1, Pages: 71-84
Abstract
The use of polymeric materials in ionexchange chromatography applications is advantageous because of their typically high mechanical stability and tolerance of a wide range of pH conditions The possibility of using polymeric monoliths in ionexchange chromatography is therefore obvious and many of the same strategies developed for polymeric particles have been adapted for use with polymeric monoliths In this review different strategies for the synthesis of polymeric monoliths with ionexchange functionality are discussed The incorporation of ionexchange functionality by copolymerization is included as also are different postpolymerization alterations to the monolith surface such as grafting The formulations and strategies presented include materials intended for use in analytical separations in ionexchange chromatography sample pretreatment or enrichment applications and materials for capillary electrochromatography Finally examples of the use of polymeric monoliths in ionexchange chromatography applications are included with examples published in the years 2003 to 2008
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