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Title of Journal: J Mater Sci

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Abbravation: Journal of Materials Science

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Springer US

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10.1007/s10164-010-0252-y

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1573-4803

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Ibuprofen loaded porous calcium phosphate nanosphe

Authors: Fengwei Shao Lin Liu Kejie Fan Yurong Cai Juming Yao
Publish Date: 2011/09/07
Volume: 47, Issue: 2, Pages: 1054-1058
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Abstract

Porous calcium phosphate nanospheres were successfully fabricated by a simple sonochemical method and used as a drug carrier of ibuprofen Morphology structure ibuprofen storage capacity and release rate of the calcium phosphate nanospheres were characterized using FESEM TEM Nitrogen adsorption XRD FTIR and UV–vis adsorption spectroscopies Results showed the obtained calcium phosphate nanospheres held a porous structure with an average diameter of 489 ± 1742 nm Moreover the porous nanospheres possessed an adjustable load amount and release rate for ibuprofen by changing drug concentrations during the drug loading process In addition the effects of size and dispersancy of porous spheres on drug release rate were discussed which was found that larger or agglomerate porous spheres could delay drug release process This study indicated that porous calcium phosphate nanospheres were a perfect drug carrier for ibuprofen which has potential application for the therapy of skeletal diseaseThis study is financially supported by the Program for New Century Excellent Talents in University NCET070763 Special Programm of National Natural Science Foundation of China Grant21041003 and Zhejiang Natural Science Foundation of China Y4090416

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  287. Cellulose film regenerated from Styela clava tunics have biodegradability, toxicity and biocompatibility in the skin of SD rats
  288. Plastic deformation mechanism of crystalline polymer materials during the rolling process
  289. Microwave dielectric properties of low-fired CoNb 2 O 6 ceramics with B 2 O 3 addition
  290. Facile synthesis of ordered mesoporous silica with high γ-Fe 2 O 3 loading via sol-gel process
  291. Newly developed biodegradable polymer nanocomposites of cellulose acetate and Al 2 O 3 nanoparticles with enhanced dielectric performance for embedded passive applications
  292. Specific heat of the Ba 0.7 Sr 0.3 Ti 1− y Zr y O ( y = 0, 0.03, 0.05, 0.1) ferroelectric ceramics obtained by the temperature relaxation method
  293. Facile synthesis of high performance non-noble-metal electrocatalyst Fe–N–S/C for oxygen reduction reaction in acidic solutions
  294. Preparation and characterization of water soluble and conducting poly(sodium 4-styrenesulfonate) doped poly(3,4-ethylenedioxythiophene)/multi-walled carbon nanotubes core–shell nanocomposites by in situ polymerization
  295. A strategy for improving mechanical properties of composite nanofibers through surface functionalization of fillers with hyperbranched polyglycerol
  296. Internal melting and coarsening of liquid droplets in an Al–Cu alloy: a 4-D experimental study
  297. Effect of water on the fatigue behaviour of a pa66/glass fibers composite material
  298. Improved magnetism in Cr doped ZnS nanoparticles with nitrogen co-doping synthesized using chemical co-precipitation technique
  299. Adsorption kinetics, isotherm, and thermodynamics of Hg 2+ to polyaniline/hexagonal mesoporous silica nanocomposite in water/wastewater
  300. Wood—a 45th anniversary review of JMS papers. Part 1: The wood cell wall and mechanical properties
  301. Preparation, in vitro and in vivo evaluation of mPEG-PLGA nanoparticles co-loaded with syringopicroside and hydroxytyrosol
  302. Phase selection of titanium boride in copper matrix composites during solidification
  303. Impact factors, citation distributions and journal stratification
  304. Effects of crosslinking ratio, model drugs, and electric field strength on electrically controlled release for alginate-based hydrogel
  305. Synthesis and lithium storage properties of interconnected fullerene-like carbon nanofibers encapsulated with tin nanoparticles
  306. Structure and crystallization behavior of borate-based bioactive glass
  307. Influence of organic salt concentration on the performance of bulk heterojunction organic solar cell
  308. Synthesis of superparamagnetic cobalt nanoparticles through solvothermal process
  309. Formation mechanism of NaNbO 3 powders during hydrothermal synthesis
  310. Development of n-type microcrystalline SiO x :H films and its application by innovative way to improve the performance of single junction µc-Si:H solar cell
  311. Development of a Sn–Ag–Cu solder reinforced with Ni-coated carbon nanotubes
  312. Oxygen incorporation in Ti 2 AlC thin films studied by electron energy loss spectroscopy and ab initio calculations
  313. Mechanical and tribological behavior of clay–polypropylene nanocomposites
  314. Development of multiferroic polymer nanocomposite from PVDF and (Bi 0.5 Ba 0.25 Sr 0.25 )(Fe 0.5 Ti 0.5 )O 3
  315. Low-temperature thermoelectric characteristics of Ca 3−x Yb x Co 3.95 Ga 0.05 O 9+δ (0 ≤ x ≤ 0.10)
  316. Rolling and recrystallisation textures in Cu–Al, Cu–Mn and Cu–Ni alloys
  317. Dissolutive wetting of Si by molten Cu
  318. Room temperature elastic moduli and Vickers hardness of hot-pressed LLZO cubic garnet
  319. Effect of the substrate temperature on the structural, optical and electrical properties of spray-deposited CdS:B films
  320. New insights into the crystallization of cordierite from a stoichiometric glass by in situ high-temperature SEM
  321. Micro-porous silicon structure with low optical reflection
  322. PEDOT:PSS/graphene/PEDOT ternary film for high performance electrochemical electrode
  323. Microstructure, electrical and magnetic properties of polycrystalline La 0.85 K 0.15 MnO 3 manganites prepared by different synthesis routes
  324. BiB 3 O 6 :Pr 3+ partially crystallized glasses for second harmonic generation
  325. Prediction models for the yield strength of particle-reinforced unimodal pure magnesium (Mg) metal matrix nanocomposites (MMNCs)
  326. An effective three-dimensional surface-enhanced Raman scattering substrate based on oblique Si nanowire arrays decorated with Ag nanoparticles
  327. High-frequency response in Sr 1−x Ca x TiO 3 powders studied by terahertz time-domain spectroscopy
  328. Structural and composition analysis of Apex™ and Foturan™ photodefinable glasses
  329. Influencing biophysical properties of fibrin with buffer solutions
  330. A new method of depositing high figure-of-merit porous PZT pyroelectric thick film using [001]-oriented PZT nanorod by electrophoresis deposition
  331. Mechanisms of stress-corrosion cracking and liquid-metal embrittlement in Al-Zn-Mg bicrystals
  332. Self-dissolving micropile array tips for percutaneous administration of insulin
  333. Investigation of Er-doped Sc 2 O 3 transparent ceramics by positron annihilation spectroscopy
  334. Electrochemical investigation of silicon/carbon composite as anode material for lithium ion batteries
  335. Low temperature sintering and properties of lead-free (Ba 0.85 Ca 0.15 )(Zr 0.1 Ti 0.9 )O 3 ceramics with Ba(Cu 0.5 W 0.5 )O 3 addition
  336. Electrical characteristics of Au/n-Si (MS) Schottky Diodes (SDs) with and without different rates (graphene + Ca 1.9 Pr 0.1 Co 4 O x -doped poly(vinyl alcohol)) interfacial layer
  337. Composition control of co-electroplating Au–Sn deposits using experimental strategies
  338. On the triggering mechanism for the metal–insulator transition in thin film VO 2 devices: electric field versus thermal effects
  339. Influence of thermal treatment on the nonlinear current–voltage behavior and restoration hysteresis effect of CaCu 3 Ti 4 O 12 thin films
  340. Dental casting alloys behaviour during power toothbrushing with toothpastes with various abrasivities. Part I: wear behavior
  341. Atomic layer deposition of hafnium oxide dielectrics on silicon and germanium substrates
  342. Size dependence of the contact angle of liquid clusters of Bi and Sn supported on SiO 2 , Al 2 O 3 , graphite, diamond and AlN
  343. Controlled fabrication of noble metal nanoparticles loaded on the surfaces of cyclotriphosphazene-containing polymer nanotubes
  344. Fabrication, chemical composition change and phase evolution of biomorphic hydroxyapatite
  345. Preparation and performance of organic–inorganic halide perovskites
  346. Fabrication of an aluminum–carbon nanotube metal matrix composite by accumulative roll-bonding
  347. Mechanical properties of chromium–chromium sulfide cermets fabricated by self-propagating high-temperature synthesis
  348. Application of power loss calculation to estimate the specific contact resistance of the screen-printed silver ohmic contacts of the large area silicon solar cells
  349. Chain flexibility versus molecular entanglement response to rubbing deformation in designing poly(oxadiazole-naphthylimide)s as liquid crystal orientation layers
  350. Improvement of photopolymer materials for holographic data storage
  351. Fabrication and characterization of Li 0.5 Fe 2.5 O 4 octahedrons via a TEA-assisted route
  352. Monoclinic effects and orthotropic estimation for the behaviour of rolled sheet
  353. Prediction of no-recrystallization temperature by simulation of multi-pass flow stress curves from single-pass curves
  354. Microstructural and electrical properties of PbTIO 3 screen-printed thick films
  355. Enhanced photocatalytic activity of Mg 0.05 Zn 0.95 O thin films prepared by sol–gel method through a cycle
  356. Using deformation mechanism maps to depict flow processes in superplastic ultrafine-grained materials
  357. Principles of grain refinement in magnesium alloys processed by equal-channel angular pressing
  358. A review of carbon dots in biological applications
  359. Methotrexate-grafted-oligochitosan micelles as drug carriers: synthesis and biological evaluations
  360. Synthesis and temperature dependent photoluminescence of Zn 1− x Mg x O films grown by ultrasonic spray pyrolysis
  361. Influence of dopants on the thermal properties and critical behavior of the ferroelectric transition in uniaxial ferroelectric Sn 2 P 2 S 6
  362. Influence of light polymerization modes on degree of conversion and crosslink density of dental composites
  363. Effect of CaF 2 on the sintering and thermal expansion of La 0.85 Sr 0.15 Cr 0.95 O 3
  364. Effect of modified MWCNT on the properties of PPO/LCP blend
  365. Effect of stacking type in precursors on composition, morphology and electrical properties of the CIGS films
  366. Equilibrium and non-equilibrium charge-dependent quantification of endothelial cell hydrogel scaffolds
  367. New insight into PEO modified inner surface of HNTs and its nano-confinement within nanotube
  368. Microstructure and wear properties of LENS ® deposited medical grade CoCrMo
  369. Reaction synthesis of in situ vanadium carbide particulates-reinforced iron matrix composites by spark plasma sintering
  370. Effects of Cr 2 O 3 doping on the microstructural and electrical properties of ZnO–Bi 2 O 3 based varistor films
  371. Diffraction-line shifts and broadenings in continuously and discontinuously coarsening precipitate-matrix systems: coarsening of initially coherent nitride precipitates in a ferrite matrix
  372. Conversion of waste animal bones into porous hydroxyapatite by alkaline treatment: effect of the impregnation ratio and investigation of the activation mechanism
  373. Nanomechanical properties of the stigma of dragonfly Anax parthenope julius Brauer
  374. Three-dimensional NiCo 2 S 4 nanosheets as high-performance electrodes materials for supercapacitors
  375. Optical characterisation of silicon nitride thin films grown by novel remote plasma sputter deposition
  376. In situ synthesis of CuS nanoparticle with a distinguishable SPR peak in NIR region
  377. First principles investigation of the structure and stability of LiNiO 2 doped with Co and Mn
  378. Preparation and characteristic of magnetic LDPE/Fe 3 O 4 nano-composite films
  379. BaTiO 3 (BTO)–CaCu 3 Ti 4 O 12 (CCTO) substrates for microwave devices and antennas
  380. Comparative study of electrical and mechanical properties of fire-refined and electrolytically refined cold-drawn copper wires
  381. Sol-gel synthesis and characterization of the photocatalyst BaCo 1/3 Nb 2/3 O 3
  382. On the use of non-MPB lead zirconium titanate (PZT) granules for piezoelectric ceramic–polymer sensorial composites
  383. The effect of photo-oxidation on thermal and fire retardancy of polypropylene nanocomposites
  384. Comparison of tensile and knot security properties of surgical sutures
  385. Precipitation behavior of Heusler phase (Ni 2 AlHf) in multiphase NiAl alloy
  386. Enhanced wear and fatigue properties of Ti–6Al–4V alloy modified by plasma carburizing/CrN coating
  387. Effect of particle surface treatment and blending method on flexural properties of injection-molded cenosphere/HDPE syntactic foams
  388. Al x (Sn 2 Se 3 ) 1−x phase change films for high-temperature data retention and fast transition speed application
  389. AFM analysis of the surface of nanoporous membranes: application to the nanofiltration of potassium clavulanate
  390. Comparison of structural, optical, photocatalytic behavior and hydrophilic properties of pure and Sn/La co-doped TiO 2 thin films
  391. Fabrication and finite element modeling of ellipsoidal macro-shells
  392. PMMA nanocomposites and gradient materials prepared by means of polysilsesquioxane (POSS) self-assembly
  393. Dielectric properties of organosilicons from first principles
  394. Effect of replacement of MgO by CaO on sintering, crystallization and properties of MgO–Al 2 O 3 –SiO 2 system glass-ceramics
  395. Supercritical CO 2 processing of polymers for the production of materials with applications in tissue engineering and drug delivery
  396. Mesoporous silica nanoparticle-functionalized poly(methyl methacrylate)-based bone cement for effective antibiotics delivery
  397. Synthesis and characterization of thin films of palladium (II) phthalocyanine and its derivatives using the thermal evaporation technique
  398. Growth and characterization of well-aligned rutile TiO 2 nanocrystals on sapphire substrates via metal organic vapour deposition
  399. Quantitative proteomics reveals altered expression of extracellular matrix related proteins of human primary dermal fibroblasts in response to sulfated hyaluronan and collagen applied as artificial extracellular matrix
  400. Anatase TiO 2 nanoparticles/carbon nanotubes nanofibers: preparation, characterization and photocatalytic properties
  401. Influence of interstitial impurities on the valence electron structures and phase transformation behavior in intermediate Ti–Al alloys
  402. Investigation of the lithium-rich boundary of the Li 1+ x Mn 2− x O 4 cubic spinel phase in air
  403. Strength of functionally designed cellular cemented carbides produced by coextrusion
  404. Fabrication of bioactive hydroxyapatite/bis-GMA based composite via three dimensional printing
  405. Fabrication of Y 2 O 2 S:Eu 3+ hollow nanofibers by sulfurization of Y 2 O 3 :Eu 3+ hollow nanofibers
  406. Organic solvent based TiO 2 dispersion paste for dye-sensitized solar cells prepared by industrial production level procedure
  407. Rietveld analysis, magnetic, vibrational and impedance properties of (Bi 1−x Pr x )(Fe 1−x Zr x )O 3 ceramics
  408. Microstructure and microwave dielectric properties of Ba 4.2 Nd 9.2 Ti 18−x Sn x O 54 (x = 0, 0.25, 0.5, 1, 1.5, 2) ceramics
  409. Influence of cross-linking density on swelling and estradiol permeation of chitosan membranes
  410. Biomechanical characterisation of a degradable magnesium-based (MgCa0.8) screw
  411. The effect of substrate temperature on the microstructure and tunnelling magnetoresistance of FeCo–Al 2 O 3 nanogranular films
  412. Low-temperature solid-state synthesis and phase-controlling studies of CdS nanoparticles
  413. Effect of buffer thickness on the properties of Al-doped ZnO thin films prepared by DC magnetron sputtering
  414. Cr(VI) removal from aqueous solution using chemically reduced and functionalized graphene oxide
  415. Investigation of the lithium-rich boundary of the Li 1+ x Mn 2− x O 4 cubic spinel phase in air
  416. Coprecipitation synthesis and optical absorption property of Zn 2 Ti x Sn 1– x O 4 (0 ≤  x ≤ 1) solid solutions
  417. Use of chitosan and β-tricalcium phosphate, alone and in combination, for bone healing in rabbits
  418. Supported and unsupported platinum catalysts prepared by a one-step dry deposition method and their oxygen reduction reactivity in acidic media
  419. Surface characterization and biological properties of regular dentin, demineralized dentin, and deproteinized dentin
  420. Structural, optical and electrical properties of gamma-rays exposed selenium nanowires
  421. Fabrication and mechanical testing of porous calcium phosphate bioceramic granules
  422. Tensile properties and fracture behaviour of carbon fibre filament materials
  423. Novel carboxymethyl chitosan-graphene oxide hybrid particles for drug delivery
  424. Influence of interfacial modification on the thermal conductivity of polymer composites
  425. l -cysteine-reduced graphene oxide/poly(vinyl alcohol) ultralight aerogel as a broad-spectrum adsorbent for anionic and cationic dyes
  426. Effects of electromigration on resistance changes in eutectic SnBi solder joints
  427. TiO 2 /porous silicon nanocomposite passivation coating for mc-Si wafers
  428. Three-dimensional nonwoven scaffolds from a novel biodegradable poly(ester amide) for tissue engineering applications
  429. Regulatory biocompatibility requirements for biomaterials used in regenerative medicine
  430. Enhancing mechanical and fracture properties of sandwich composites using nanoparticle reinforcement
  431. Interfacial microstructure and hardness of nickel (Ni) nanoparticle-doped tin–silver–copper (Sn–Ag–Cu) solders on immersion silver (Ag)-plated copper (Cu) substrates
  432. Fabrication and characterization of La 0.6 Sr 0.4 Co 0.2 Fe 0.8 O 3-δ (LSCF)-Ce 0.9 Gd 0.1 O 1.95 (GDC) composite thick film for anode supported solid oxide fuel cells
  433. Synthesis of doubly functional nanowhiskers from a colloid solution including a V–Ti complex precursor
  434. Synthesis and properties of ellipsoidal hematite/silicone core-shell particles
  435. Impedance spectroscopy study of TiO 2 addition on the ceramic matrix Na 2 Nb 4 O 11
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